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Biochemical Society Transactions|August 12, 2022
Revisiting PARP2 and PARP1 trapping through quantitative live-cell imagingHanwen Zhang, Xiaohui Lin, Shan ZhaDNA Repair|June 1, 2024
The dynamics and regulation of PARP1 and PARP2 in response to DNA damage and during replicationHanwen Zhang, Shan ZhaScience Advances|March 24, 2023
Clinical PARP inhibitors allosterically induce PARP2 retention on DNAMarie-France Langelier, Xiaohui Lin, Shan Zha, et al.Proceedings of the National Academy of Sciences of the United States of America|July 24, 2023
Inactive PARP1 causes embryonic lethality and genome instability in a dominant-negative mannerZhengping Shao, Brian J Lee, Hanwen Zhang, et al.Nucleic Acids Research|July 9, 2026
Ku70-SAP domain has an overlapping function with DNA-PKcs in limiting the lateral movement of the Ku ring along DNAYimeng Zhu, Sagun Jonchhe, Hanwen Zhang, et al.Biorxiv : the Preprint Server for Biology|March 27, 2026
PARG inhibition sequesters nuclear PAR-binding proteins, including XRCC1 and its partners, into nuclear condensates to elicit cytotoxicityIsaac Dumoulin, Brian J Lee, Chuhan Zhang, et al.Nucleic Acids Research|March 29, 2022
PARP inhibitors trap PARP2 and alter the mode of recruitment of PARP2 at DNA damage sitesXiaohui Lin, Wenxia Jiang, Johannes Rudolph, et al.Biorxiv : the Preprint Server for Biology|May 27, 2024
XRCC1 mediates PARP1- and PAR-dependent recruitment of PARP2 to DNA damage sitesXiaohui Lin, Kay Sze Karina Leung, Kaitlynn F Wolfe, et al.Journal of Immunology (Baltimore, Md. : 1950)|May 19, 2019
Phosphorylation at S2053 in Murine (S2056 in Human) DNA-PKcs Is Dispensable for Lymphocyte Development and Class Switch RecombinationWenxia Jiang, Verna M Estes, Xiaobin S Wang, et al.Biorxiv : the Preprint Server for Biology|September 10, 2024
The KU70-SAP domain has an overlapping function with DNA-PKcs in limiting the lateral movement of KU along DNAYimeng Zhu, Brian J Lee, Shingo Fujii, et al.Pageof 83