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The Biochemical Journal|May 24, 2024
RNA processing by the CRISPR-associated NYN ribonucleaseHaotian Chi, Malcolm F White
The Biochemical Journal|March 30, 2026
The CRISPR ring nuclease Csx15 oligomerises on cyclic nucleotide binding to regulate antiviral defenceMalcolm F White, Stephen A McMahon, Haotian Chi, et al.
Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences|September 4, 2025
Diversity and abundance of ring nucleases in type III CRISPR-Cas lociVille Hoikkala, Haotian Chi, Sabine Grüschow, et al.
The Biochemical Journal|November 5, 2025
A viral SAVED protein with ring nuclease activity degrades the CRISPR second messenger cA4Marta Orzechowski, Ville Hoikkala, Haotian Chi, et al.
Nature|October 18, 2023
Antiviral type III CRISPR signalling via conjugation of ATP and SAMHaotian Chi, Ville Hoikkala, Sabine Grüschow, et al.
Nature Communications|December 15, 2025
Structure and mechanism of the broad spectrum CRISPR-associated ring nuclease Crn4Haotian Chi, Ville Hoikkala, Stephen McMahon, et al.
Nucleic Acids Research|July 12, 2025
SAM-AMP lyases in type III CRISPR defenceHaotian Chi, Stephen McMahon, Lukas Daniel-Pedersen, et al.
Biochemical Society Transactions|January 27, 2011
Homologous recombination in the archaea: the means justify the endsMalcolm F White
Cell|July 11, 2020
Bacteria SAVED from VirusesMalcolm F White
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