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Journal of Psychopharmacology (Oxford, England)|December 4, 2020
Presynaptic vesicular accumulation is required for antipsychotic efficacy in psychotic-like ratsTaygun C Uzuneser, Eva-Maria Weiss, Jana Dahlmanns, et al.
Nature Communications|November 18, 2024
A bitter anti-inflammatory drug binds at two distinct sites of a human bitter taste GPCRLior Peri, Donna Matzov, Dominic R Huxley, et al.
Nature Communications|April 14, 2023
Constrained catecholamines gain β<sub>2</sub>AR selectivity through allosteric effects on pocket dynamicsXinyu Xu, Jeremy Shonberg, Jonas Kaindl, et al.
Journal of Medicinal Chemistry|October 15, 2019
Dual-Acting Cholinesterase-Human Cannabinoid Receptor 2 Ligands Show Pronounced Neuroprotection in Vitro and Overadditive and Disease-Modifying Neuroprotective Effects in VivoMatthias Scheiner, Dominik Dolles, Sandra Gunesch, et al.
Nature Chemical Biology|June 3, 2020
An allosteric modulator binds to a conformational hub in the β<sub>2</sub> adrenergic receptorXiangyu Liu, Jonas Kaindl, Magdalena Korczynska, et al.
Journal of Medicinal Chemistry|September 11, 2024
Dually Labeled Neurotensin NTS<sub>1</sub>R Ligands for Probing Radiochemical and Fluorescence-Based Binding AssaysFabian J Ertl, Sergei Kopanchuk, Nicola C Dijon, et al.
Nature|November 22, 2013
Activation and allosteric modulation of a muscarinic acetylcholine receptorAndrew C Kruse, Aaron M Ring, Aashish Manglik, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 9, 2018
Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonistsHongtao Liu, Josefa Hofmann, Inbar Fish, et al.
Nature|August 18, 2016
Structure-based discovery of opioid analgesics with reduced side effectsAashish Manglik, Henry Lin, Dipendra K Aryal, et al.
Science Advances|June 18, 2025
Discovery of a functionally selective serotonin receptor (5-HT<sub>1A</sub>R) agonist for the treatment of painAnnika Ullrich, Johannes Schneider, João M Braz, et al.
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