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Clinical Pharmacology and Therapeutics|March 19, 2024
Clinical Pharmacology Considerations for the "Off-the-Shelf" Allogeneic Cell TherapiesHardik Mody, Dhruvitkumar S Sutaria, Dale MilesScientific Reports|February 22, 2023
In vitro to clinical translational pharmacokinetic/pharmacodynamic modeling of doxorubicin (DOX) and dexrazoxane (DEX) interactions: Safety assessment and optimizationHardik Mody, Tanaya R Vaidya, Sihem Ait-OudhiaBreast Cancer (Dove Medical Press)|December 17, 2019
Chloroquine sensitizes MDA-MB-231 cells to osimertinib through autophagy-apoptosis crosstalk pathwayBrett Fleisher, Hardik Mody, Carolin Werkman, et al.Cells|January 8, 2023
Pharmacodynamic Modeling to Evaluate the Impact of Cimetidine, an OCT2 Inhibitor, on the Anticancer Effects of CisplatinHardik Mody, Tanaya R Vaidya, Lawrence J Lesko, et al.CPT: Pharmacometrics & Systems Pharmacology|July 27, 2025
Mitigating Trastuzumab-Doxorubicin Cardiotoxicity With Multiscale Quantitative Systems Toxicology and PBPK-Toxicodynamic Predictive Modeling FrameworkSijia Yu, Hardik Mody, Tanaya R Vaidya, et al.Frontiers in Pharmacology|November 6, 2023
In vitro to clinical translation of combinatorial effects of doxorubicin and dexrazoxane in breast cancer: a mechanism-based pharmacokinetic/pharmacodynamic modeling approachHardik Mody, Tanaya R Vaidya, Jovin Lezeau, et al.The AAPS Journal|January 6, 2021
Multiscale and Translational Quantitative Systems Toxicology, Pharmacokinetic-Toxicodynamic Modeling Analysis for Assessment of Doxorubicin-Induced CardiotoxicityTanaya R Vaidya, Hardik Mody, Yesenia L Franco, et al.Journal of Pharmacokinetics and Pharmacodynamics|January 3, 2021
A quantitative systems pharmacological approach identified activation of JNK signaling pathway as a promising treatment strategy for refractory HER2 positive breast cancerYesenia L Franco, Vidya Ramakrishnan, Tanaya R Vaidya, et al.Journal of Pharmaceutical Sciences|November 22, 2023
Identification of Novel and Early Biomarkers for Cisplatin-induced Nephrotoxicity and the Nephroprotective Role of Cimetidine using a Pharmacometabolomic-based Approach Coupled with In Vitro Toxicodynamic Modeling and SimulationHardik Mody, Sreenath Nair, Adrian Rump, et al.Clinical Pharmacology in Drug Development|October 7, 2020
A Review on Drug-Induced Nephrotoxicity: Pathophysiological Mechanisms, Drug Classes, Clinical Management, and Recent Advances in Mathematical Modeling and Simulation ApproachesHardik Mody, Vidya Ramakrishnan, Maher Chaar, et al.Pageof 2