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CPT: Pharmacometrics & Systems Pharmacology|February 10, 2021
Bench-to-bedside translation of chimeric antigen receptor (CAR) T cells using a multiscale systems pharmacokinetic-pharmacodynamic model: A case study with anti-BCMA CAR-TAman P Singh, Wenbo Chen, Xirong Zheng, et al.Cancer Letters|January 21, 2015
Defective hCNT1 transport contributes to gemcitabine chemoresistance in ovarian cancer subtypes: overcoming transport defects using a nanoparticle approachSau Wai Hung, Sean Marrache, Shannon Cummins, et al.Clinical Pharmacology and Therapeutics|March 7, 2024
Clinical Pharmacology Perspective on Development of Adeno-Associated Virus Vector-Based Retina Gene TherapyJennifer Lynn Ford, Eleni Karatza, Hardik Mody, et al.Clinical Pharmacology and Therapeutics|October 1, 2020
Model-Based Cellular Kinetic Analysis of Chimeric Antigen Receptor-T Cells in HumansCan Liu, Vivaswath S Ayyar, Xirong Zheng, et al.Plos One|August 14, 2013
Pharmacological reversal of histone methylation presensitizes pancreatic cancer cells to nucleoside drugs: in vitro optimization and novel nanoparticle delivery studiesSau Wai Hung, Hardik Mody, Sean Marrache, et al.Clinical Pharmacology and Therapeutics|July 2, 2023
Best Practices and Considerations for Clinical Pharmacology and Pharmacometric Aspects for Optimal Development of CAR-T and TCR-T Cell Therapies: An Industry PerspectiveHardik Mody, Ken Ogasawara, Xu Zhu, et al.Clinical Pharmacology and Therapeutics|November 20, 2023
An IQ Consortium Perspective on Best Practices for Bioanalytical and Immunogenicity Assessment Aspects of CAR-T and TCR-T Cellular Therapies DevelopmentJochem Gokemeijer, Nanda Balasubramanian, Ken Ogasawara, et al.Lupus Science & Medicine|June 17, 2026
Phase Ib, multicentre, open-label, dose-escalation study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of subcutaneously administered mosunetuzumab in participants with systemic lupus erythematosusElsa Martins, Vishala L Chindalore, X Rebecca Sheng, et al.Clinical Pharmacology and Therapeutics|September 19, 2024
Industry Perspective on First-in-Human and Clinical Pharmacology Strategies to Support Clinical Development of T-Cell Engaging Bispecific Antibodies for Cancer TherapyPrathap Nagaraja Shastri, Nirav Shah, Martin Lechmann, et al.The AAPS Journal|July 31, 2023
PK/PD and Bioanalytical Considerations of AAV-Based Gene Therapies: an IQ Consortium Industry Position PaperUma Kavita, Kefeng Sun, Manuela Braun, et al.Pageof 2