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Bioorganic & Medicinal Chemistry Letters|August 26, 2009
Novel CGRP receptor antagonists through a design strategy of target simplification with addition of molecular flexibilityMichael R Wood, Kathy M Schirripa, June J Kim, et al.Journal of Medicinal Chemistry|December 4, 2003
Synthesis and evaluation of imidazole acetic acid inhibitors of activated thrombin-activatable fibrinolysis inhibitor as novel antithromboticsJames C Barrow, Philippe G Nantermet, Shaun R Stauffer, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of MK-3207: A Highly Potent, Orally Bioavailable CGRP Receptor AntagonistIan M Bell, Steven N Gallicchio, Michael R Wood, et al.Journal of Medicinal Chemistry|September 6, 2019
Discovery of MK-8719, a Potent O-GlcNAcase Inhibitor as a Potential Treatment for TauopathiesHarold G Selnick, J Fred Hess, Cuyue Tang, et al.Journal of Medicinal Chemistry|December 8, 2006
Discovery of oxadiazoyl tertiary carbinamine inhibitors of beta-secretase (BACE-1)Hemaka A Rajapakse, Philippe G Nantermet, Harold G Selnick, et al.Bioorganic & Medicinal Chemistry Letters|May 22, 2012
MK-8825: a potent and selective CGRP receptor antagonist with good oral activity in ratsIan M Bell, Craig A Stump, Steven N Gallicchio, et al.Bioorganic & Medicinal Chemistry Letters|January 30, 2007
Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind beta-secretase in a N-terminal 10s-loop down conformationShaun R Stauffer, Matthew G Stanton, Alison R Gregro, et al.Bioorganic & Medicinal Chemistry Letters|March 20, 2010
Identification of potent, highly constrained CGRP receptor antagonistsCraig A Stump, Ian M Bell, Rodney A Bednar, et al.Bioorganic & Medicinal Chemistry Letters|May 8, 2007
Design, synthesis, and SAR of macrocyclic tertiary carbinamine BACE-1 inhibitorsStacey R Lindsley, Keith P Moore, Hemaka A Rajapakse, et al.Bioorganic & Medicinal Chemistry Letters|September 5, 2024
Invention of novel 3-aminopiperidin-2-ones as calcitonin gene-related peptide receptor antagonistsDonnette D Staas, Ian M Bell, Christopher S Burgey, et al.Pageof 4