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Bioorganic & Medicinal Chemistry Letters|February 24, 2010
SAR of tertiary carbinamine derived BACE1 inhibitors: role of aspartate ligand amine pKa in enzyme inhibitionHemaka A Rajapakse, Philippe G Nantermet, Harold G Selnick, et al.
The Journal of Pharmacology and Experimental Therapeutics|January 13, 2010
Pharmacological properties of MK-3207, a potent and orally active calcitonin gene-related peptide receptor antagonistChristopher A Salvatore, Eric L Moore, Amy Calamari, et al.
Journal of Medicinal Chemistry|September 25, 2008
Discovery and X-ray crystallographic analysis of a spiropiperidine iminohydantoin inhibitor of beta-secretaseJames C Barrow, Shaun R Stauffer, Kenneth E Rittle, et al.
Bioorganic & Medicinal Chemistry Letters|May 25, 2005
P2 pyridine N-oxide thrombin inhibitors: a novel peptidomimetic scaffoldPhilippe G Nantermet, Christopher S Burgey, Kyle A Robinson, et al.
The Journal of Pharmacology and Experimental Therapeutics|June 5, 2020
MK-8719, a Novel and Selective O-GlcNAcase Inhibitor That Reduces the Formation of Pathological Tau and Ameliorates Neurodegeneration in a Mouse Model of TauopathyXiaohai Wang, Wenping Li, Jacob Marcus, et al.
Bioorganic & Medicinal Chemistry Letters|August 2, 2015
Novel oxazolidinone calcitonin gene-related peptide (CGRP) receptor antagonists for the acute treatment of migraineBrendan M Crowley, Craig A Stump, Diem N Nguyen, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
[(11)C]MK-4232: The First Positron Emission Tomography Tracer for the Calcitonin Gene-Related Peptide ReceptorIan M Bell, Steven N Gallicchio, Craig A Stump, et al.
Journal of Medicinal Chemistry|May 28, 2004
Discovery and evaluation of potent P1 aryl heterocycle-based thrombin inhibitorsMary Beth Young, James C Barrow, Kristen L Glass, et al.
Journal of Medicinal Chemistry|April 2, 2005
9-hydroxyazafluorenes and their use in thrombin inhibitorsKenneth J Stauffer, Peter D Williams, Harold G Selnick, et al.
Bioorganic & Medicinal Chemistry Letters|July 22, 2015
Methyl-substitution of an iminohydantoin spiropiperidine β-secretase (BACE-1) inhibitor has a profound effect on its potencyMelissa Egbertson, Georgia B McGaughey, Steven M Pitzenberger, et al.
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