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The Journal of Pharmacology and Experimental Therapeutics|August 27, 2013
In vivo quantification of calcitonin gene-related peptide receptor occupancy by telcagepant in rhesus monkey and human brain using the positron emission tomography tracer [11C]MK-4232Eric D Hostetler, Aniket D Joshi, Sandra Sanabria-Bohórquez, et al.Bioorganic & Medicinal Chemistry Letters|March 27, 2003
Pharmacokinetic optimization of 3-amino-6-chloropyrazinone acetamide thrombin inhibitors. Implementation of P3 pyridine N-oxides to deliver an orally bioavailable series containing P1 N-benzylamidesChristopher S Burgey, Kyle A Robinson, Terry A Lyle, et al.The Journal of Pharmacology and Experimental Therapeutics|October 16, 2008
First demonstration of cerebrospinal fluid and plasma A beta lowering with oral administration of a beta-site amyloid precursor protein-cleaving enzyme 1 inhibitor in nonhuman primatesSethu Sankaranarayanan, Marie A Holahan, Dennis Colussi, et al.Pageof 4