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Harold Kohn

Showing results (41-50 of 54) with videos related to

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ACS Chemical Neuroscience|March 21, 2013
Discovery of lacosamide affinity bait agents that exhibit potent voltage-gated sodium channel blocking propertiesKi Duk Park, Xiao-Fang Yang, Hyosung Lee, et al.
Journal of Medicinal Chemistry|June 19, 2013
(Biphenyl-4-yl)methylammonium chlorides: potent anticonvulsants that modulate Na+ currentsHyosung Lee, Ki Duk Park, Xiao-Fang Yang, et al.
ACS Chemical Neuroscience|May 3, 2011
Development and characterization of novel derivatives of the antiepileptic drug lacosamide that exhibit far greater enhancement in slow inactivation of voltage-gated sodium channelsYuying Wang, Ki Duk Park, Christophe Salome, et al.
Bioorganic & Medicinal Chemistry|May 2, 2012
Synthesis, anticonvulsant activity, and neuropathic pain-attenuating activity of N-benzyl 2-amino-2-(hetero)aromatic acetamidesPranjal K Baruah, Jason Dinsmore, Amber M King, et al.
Journal of Medicinal Chemistry|January 1, 2010
Synthesis and anticonvulsant activities of (R)-N-(4'-substituted)benzyl 2-acetamido-3-methoxypropionamidesChristophe Salomé, Elise Salomé-Grosjean, Ki Duk Park, et al.
Journal of Medicinal Chemistry|June 7, 2011
Primary amino acid derivatives: compounds with anticonvulsant and neuropathic pain protection activitiesAmber M King, Christophe Salomé, Jason Dinsmore, et al.
Biochemistry|February 3, 2005
The 1.9 A crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active sitePierre LeMagueres, Hookang Im, Jerry Ebalunode, et al.
Journal of Medicinal Chemistry|August 25, 2011
Primary amino acid derivatives: substitution of the 4'-N'-benzylamide site in (R)-N'-benzyl 2-amino-3-methylbutanamide, (R)-N'-benzyl 2-amino-3,3-dimethylbutanamide, and (R)-N'-benzyl 2-amino-3-methoxypropionamide provides potent anticonvulsants with pain-attenuating propertiesAmber M King, Christophe Salomé, Elise Salomé-Grosjean, et al.
Epilepsy Research|April 17, 2007
Lacosamide, a novel anti-convulsant drug, shows efficacy with a wide safety margin in rodent models for epilepsyThomas Stöhr, Harvey J Kupferberg, James P Stables, et al.
ACS Chemical Neuroscience|November 25, 2014
Chimeric agents derived from the functionalized amino acid, lacosamide, and the α-aminoamide, safinamide: evaluation of their inhibitory actions on voltage-gated sodium channels, and antiseizure and antinociception activities and comparison with lacosamide and safinamideKi Duk Park, Xiao-Fang Yang, Erik T Dustrude, et al.
Pageof 6

Showing results (41-50 of 54) with videos related to

Sort By:
Pageof 6
ACS Chemical Neuroscience|March 21, 2013
Discovery of lacosamide affinity bait agents that exhibit potent voltage-gated sodium channel blocking propertiesKi Duk Park, Xiao-Fang Yang, Hyosung Lee, et al.
Journal of Medicinal Chemistry|June 19, 2013
(Biphenyl-4-yl)methylammonium chlorides: potent anticonvulsants that modulate Na+ currentsHyosung Lee, Ki Duk Park, Xiao-Fang Yang, et al.
ACS Chemical Neuroscience|May 3, 2011
Development and characterization of novel derivatives of the antiepileptic drug lacosamide that exhibit far greater enhancement in slow inactivation of voltage-gated sodium channelsYuying Wang, Ki Duk Park, Christophe Salome, et al.
Bioorganic & Medicinal Chemistry|May 2, 2012
Synthesis, anticonvulsant activity, and neuropathic pain-attenuating activity of N-benzyl 2-amino-2-(hetero)aromatic acetamidesPranjal K Baruah, Jason Dinsmore, Amber M King, et al.
Journal of Medicinal Chemistry|January 1, 2010
Synthesis and anticonvulsant activities of (R)-N-(4'-substituted)benzyl 2-acetamido-3-methoxypropionamidesChristophe Salomé, Elise Salomé-Grosjean, Ki Duk Park, et al.
Journal of Medicinal Chemistry|June 7, 2011
Primary amino acid derivatives: compounds with anticonvulsant and neuropathic pain protection activitiesAmber M King, Christophe Salomé, Jason Dinsmore, et al.
Biochemistry|February 3, 2005
The 1.9 A crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active sitePierre LeMagueres, Hookang Im, Jerry Ebalunode, et al.
Journal of Medicinal Chemistry|August 25, 2011
Primary amino acid derivatives: substitution of the 4'-N'-benzylamide site in (R)-N'-benzyl 2-amino-3-methylbutanamide, (R)-N'-benzyl 2-amino-3,3-dimethylbutanamide, and (R)-N'-benzyl 2-amino-3-methoxypropionamide provides potent anticonvulsants with pain-attenuating propertiesAmber M King, Christophe Salomé, Elise Salomé-Grosjean, et al.
Epilepsy Research|April 17, 2007
Lacosamide, a novel anti-convulsant drug, shows efficacy with a wide safety margin in rodent models for epilepsyThomas Stöhr, Harvey J Kupferberg, James P Stables, et al.
ACS Chemical Neuroscience|November 25, 2014
Chimeric agents derived from the functionalized amino acid, lacosamide, and the α-aminoamide, safinamide: evaluation of their inhibitory actions on voltage-gated sodium channels, and antiseizure and antinociception activities and comparison with lacosamide and safinamideKi Duk Park, Xiao-Fang Yang, Erik T Dustrude, et al.
Pageof 6