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Biomolecules|June 26, 2025
Docking Simulations of G-Protein Coupled Receptors Uncover Crossover Binding Patterns of Diverse Ligands to Angiotensin, Alpha-Adrenergic and Opioid Receptors: Implications for Cardiovascular Disease and AddictionHarry Ridgway, Graham J Moore, Laura Kate Gadanec, et al.
Brain Sciences|April 21, 2022
The Human Myelin Proteome and Sub-Metalloproteome Interaction Map: Relevance to Myelin-Related Neurological DiseasesChristos T Chasapis, Konstantinos Kelaidonis, Harry Ridgway, et al.
Molecules (Basel, Switzerland)|June 13, 2025
Gating Mechanism for Biased Agonism at Angiotensin II Type 1 ReceptorsGraham J Moore, Harry Ridgway, Laura Kate Gadanec, et al.
Molecules (Basel, Switzerland)|August 12, 2022
Actions of Novel Angiotensin Receptor Blocking Drugs, Bisartans, Relevant for COVID-19 Therapy: Biased Agonism at Angiotensin Receptors and the Beneficial Effects of Neprilysin in the Renin Angiotensin SystemGraham J Moore, Harry Ridgway, Konstantinos Kelaidonis, et al.
Viruses|November 27, 2024
Computational Evidence for Bisartan Arginine Blockers as Next-Generation Pan-Antiviral Therapeutics Targeting SARS-CoV-2, Influenza, and Respiratory Syncytial VirusesHarry Ridgway, Vasso Apostolopoulos, Graham J Moore, et al.
Viruses|May 28, 2022
Understanding the Driving Forces That Trigger Mutations in SARS-CoV-2: Mutational Energetics and the Role of Arginine Blockers in COVID-19 TherapyHarry Ridgway, Christos T Chasapis, Konstantinos Kelaidonis, et al.
Computational and Structural Biotechnology Journal|October 11, 2023
W254 in furin functions as a molecular gate promoting anti-viral drug binding: Elucidation of putative drug tunneling and docking by non-equilibrium molecular dynamicsHarry Ridgway, John D Orbell, Minos-Timotheos Matsoukas, et al.
Proteomes|June 27, 2023
Network-Based Prediction of Side Effects of Repurposed Antihypertensive Sartans against COVID-19 via Proteome and Drug-Target InteractomesDespoina P Kiouri, Charalampos Ntallis, Konstantinos Kelaidonis, et al.
Viruses|February 28, 2023
Molecular Epidemiology of SARS-CoV-2: The Dominant Role of Arginine in Mutations and InfectivityHarry Ridgway, Charalampos Ntallis, Christos T Chasapis, et al.
International Journal of Molecular Sciences|May 13, 2023
Computational and Enzymatic Studies of Sartans in SARS-CoV-2 Spike RBD-ACE2 Binding: The Role of Tetrazole and Perspectives as Antihypertensive and COVID-19 TherapeuticsKonstantinos Kelaidonis, Irene Ligielli, Spiros Letsios, et al.
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