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Hepatology (Baltimore, Md.)|June 8, 2013
Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen-induced hepatocyte necrosis in miceAnup Ramachandran, Mitchell R McGill, Yuchao Xie, et al.
Toxicology Letters|December 8, 2020
Mitochondrial protein adduct and superoxide generation are prerequisites for early activation of c-jun N-terminal kinase within the cytosol after an acetaminophen overdose in miceNga T Nguyen, Kuo Du, Jephte Y Akakpo, et al.
Livers|July 15, 2024
Translocation of Adenosine A2B Receptor to Mitochondria Influences Cytochrome P450 2E1 Activity after Acetaminophen OverdoseGiselle Sanchez-Guerrero, David S Umbaugh, Abhay A Ramachandran, et al.
Toxicology and Applied Pharmacology|November 6, 2020
4-methylpyrazole protects against acetaminophen-induced acute kidney injuryJephte Y Akakpo, Anup Ramachandran, Hilmi Orhan, et al.
Toxicology Letters|November 18, 2018
Role of extracellular vesicles in release of protein adducts after acetaminophen-induced liver injury in mice and humansLuqi Duan, Anup Ramachandran, Jephte Y Akakpo, et al.
Toxicology and Applied Pharmacology|March 31, 2015
Inhibitor of apoptosis signal-regulating kinase 1 protects against acetaminophen-induced liver injuryYuchao Xie, Anup Ramachandran, David G Breckenridge, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|February 22, 2025
Mixed lineage kinase domain-like protein deficiency exacerbates early injury in a mouse model of acetaminophen hepatotoxicityGiselle Sanchez-Guerrero, David S Umbaugh, Sawyer H Smith, et al.
Archives of Toxicology|August 22, 2021
Delayed administration of N-acetylcysteine blunts recovery after an acetaminophen overdose unlike 4-methylpyrazoleJephte Y Akakpo, Matthew W Jaeschke, Anup Ramachandran, et al.
Hepatology (Baltimore, Md.)|February 15, 2011
HepaRG cells: a human model to study mechanisms of acetaminophen hepatotoxicityMitchell R McGill, Hui-Min Yan, Anup Ramachandran, et al.
Archives of Toxicology|January 18, 2021
Impaired protein adduct removal following repeat administration of subtoxic doses of acetaminophen enhances liver injury in fed miceNga T Nguyen, Jephte Y Akakpo, James L Weemhoff, et al.
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