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Expert Opinion on Drug Discovery|May 27, 2014
Discovery and preclinical development of vismodegibStephen E Gould, Jennifer A Low, James C Marsters, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 11, 2012
Evaluation of metabolism and disposition of GDC-0152 in rats using 14C labeling strategy at two different positions: a novel formation of hippuric acid from 4-phenyl-5-amino-1,2,3-thiadiazoleQin Yue, Teresa Mulder, Patrick J Rudewicz, et al.
The Journal of Pharmacology and Experimental Therapeutics|March 22, 2003
Receptor occupancy of nonpeptide corticotropin-releasing factor 1 antagonist DMP696: correlation with drug exposure and anxiolytic efficacyYu-Wen Li, Geraldine Hill, Harvey Wong, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 15, 2007
6-Hydroxybuspirone is a major active metabolite of buspirone: assessment of pharmacokinetics and 5-hydroxytryptamine1A receptor occupancy in ratsHarvey Wong, Randy C Dockens, Lori Pajor, et al.
Bioorganic & Medicinal Chemistry Letters|November 22, 2005
Synthesis and evaluation of 2-anilino-3-phenylsulfonyl-6-methylpyridines as corticotropin-releasing factor1 receptor ligandsRichard A Hartz, Argyrios G Arvanitis, Charles Arnold, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|October 17, 2009
Comparative biotransformation of pyrazinone-containing corticotropin-releasing factor receptor-1 antagonists: minimizing the reactive metabolite formationXiaoliang Zhuo, Richard A Hartz, Joanne J Bronson, et al.
Biomaterials|September 2, 2022
Chemically engineering the drug release rate of a PEG-paclitaxel conjugate using click and steric hindrance chemistries for optimal efficacyAnne Nguyen, Po-Han Chao, Chun Yat Ong, et al.
The AAPS Journal|March 5, 2013
In vitro and in vivo evaluation of amorphous solid dispersions generated by different bench-scale processes, using griseofulvin as a model compoundPo-Chang Chiang, Yong Cui, Yingqing Ran, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 3, 2011
Absorption, distribution, metabolism, and excretion of [¹⁴C]GDC-0449 (vismodegib), an orally active hedgehog pathway inhibitor, in rats and dogs: a unique metabolic pathway via pyridine ring openingQin Yue, Yung-Hsiang Chen, Teresa Mulder, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|June 1, 2012
Antitumor activity of targeted and cytotoxic agents in murine subcutaneous tumor models correlates with clinical responseHarvey Wong, Edna F Choo, Bruno Alicke, et al.
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