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Journal of Medicinal Chemistry|April 30, 2004
N-phenylphenylglycines as novel corticotropin releasing factor receptor antagonistsValentina Molteni, Julie Penzotti, Dean M Wilson, et al.Bioorganic & Medicinal Chemistry Letters|August 16, 2016
Discovery of oxa-sultams as RORc inverse agonists showing reduced lipophilicity, improved selectivity and favorable ADME propertiesOlivier René, Benjamin P Fauber, Adrian Barnard, et al.Journal of Medicinal Chemistry|July 5, 2022
Design and Measurement of Drug Tissue Concentration Asymmetry and Tissue Exposure-Effect (Tissue PK-PD) EvaluationRichard Zang, Aline Barth, Harvey Wong, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 22, 2010
Interplay of dissolution, solubility, and nonsink permeation determines the oral absorption of the Hedgehog pathway inhibitor GDC-0449 in dogs: an investigation using preclinical studies and physiologically based pharmacokinetic modelingHarvey Wong, Frank-Peter Theil, Yong Cui, et al.Toxicological Sciences : an Official Journal of the Society of Toxicology|January 28, 2005
Increased hepatobiliary clearance of unconjugated thyroxine determines DMP 904-induced alterations in thyroid hormone homeostasis in ratsHarvey Wong, Lois D Lehman-McKeeman, Mary F Grubb, et al.Journal of Medicinal Chemistry|March 29, 2011
Identification, characterization, and implications of species-dependent plasma protein binding for the oral Hedgehog pathway inhibitor vismodegib (GDC-0449)Anthony M Giannetti, Harvey Wong, Gerrit J P Dijkgraaf, et al.Journal of Medicinal Chemistry|February 21, 2009
Orally bioavailable antagonists of inhibitor of apoptosis proteins based on an azabicyclooctane scaffoldFrederick Cohen, Bruno Alicke, Linda O Elliott, et al.Bioorganic & Medicinal Chemistry Letters|November 19, 2013
Structure-based design of substituted hexafluoroisopropanol-arylsulfonamides as modulators of RORcBenjamin P Fauber, Gladys de Leon Boenig, Brenda Burton, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|January 7, 2014
Investigations into the mechanisms of pyridine ring cleavage in vismodegibS Cyrus Khojasteh, Qin Yue, Shuguang Ma, et al.Journal of Pharmaceutical Sciences|January 15, 2019
Cyclodextrin Reduces Intravenous Toxicity of a Model CompoundPriscilla Mantik, Minli Xie, Harvey Wong, et al.Pageof 11