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Pharmacology Research & Perspectives
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December 7, 2018
Risdiplam distributes and increases SMN protein in both the central nervous system and peripheral organs
Agnès Poirier, Marla Weetall, Katja Heinig, et al.
Human Molecular Genetics
|
January 14, 2016
Pharmacologically induced mouse model of adult spinal muscular atrophy to evaluate effectiveness of therapeutics after disease onset
Zhihua Feng, Karen K Y Ling, Xin Zhao, et al.
Human Molecular Genetics
|
November 17, 2020
Corrigendum to: Pharmacologically-induced mouse model of adult spinal muscular atrophy to evaluate effectiveness of therapeutics after disease onset
Zhihua Feng, Karen K Y Ling, Xin Zhao, et al.
Frontiers in Pharmacology
|
June 15, 2026
Pharmacology of nivegacetor (RG6289), a potent and selective gamma secretase modulator in clinical development for the treatment of Alzheimer's disease
Lothar Lindemann, Julie Lambotte, Judith Rothe, et al.
British Journal of Clinical Pharmacology
|
October 11, 2018
A phase 1 healthy male volunteer single escalating dose study of the pharmacokinetics and pharmacodynamics of risdiplam (RG7916, RO7034067), a SMN2 splicing modifier
Stefan Sturm, Andreas Günther, Birgit Jaber, et al.
ACS Medicinal Chemistry Letters
|
June 20, 2020
Discovery of RO7185876, a Highly Potent γ-Secretase Modulator (GSM) as a Potential Treatment for Alzheimer's Disease
Hasane Ratni, Andre Alker, Bjoern Bartels, et al.
Journal of Medicinal Chemistry
|
January 18, 2020
Discovery of Balovaptan, a Vasopressin 1a Receptor Antagonist for the Treatment of Autism Spectrum Disorder
Patrick Schnider, Caterina Bissantz, Andreas Bruns, et al.
Human Molecular Genetics
|
August 9, 2021
SMN protein is required throughout life to prevent spinal muscular atrophy disease progression
Xin Zhao, Zhihua Feng, Nicole Risher, et al.
Human Molecular Genetics
|
March 3, 2016
Pharmacokinetics, pharmacodynamics, and efficacy of a small-molecule SMN2 splicing modifier in mouse models of spinal muscular atrophy
Xin Zhao, Zhihua Feng, Karen K Y Ling, et al.
Journal of Medicinal Chemistry
|
June 15, 2016
Specific Correction of Alternative Survival Motor Neuron 2 Splicing by Small Molecules: Discovery of a Potential Novel Medicine To Treat Spinal Muscular Atrophy
Hasane Ratni, Gary M Karp, Marla Weetall, et al.
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of 3
Search research articles
Search
Showing results (11-20 of 24) with videos related to
Sort By:
Page
of 3
Pharmacology Research & Perspectives
|
December 7, 2018
Risdiplam distributes and increases SMN protein in both the central nervous system and peripheral organs
Agnès Poirier, Marla Weetall, Katja Heinig, et al.
Human Molecular Genetics
|
January 14, 2016
Pharmacologically induced mouse model of adult spinal muscular atrophy to evaluate effectiveness of therapeutics after disease onset
Zhihua Feng, Karen K Y Ling, Xin Zhao, et al.
Human Molecular Genetics
|
November 17, 2020
Corrigendum to: Pharmacologically-induced mouse model of adult spinal muscular atrophy to evaluate effectiveness of therapeutics after disease onset
Zhihua Feng, Karen K Y Ling, Xin Zhao, et al.
Frontiers in Pharmacology
|
June 15, 2026
Pharmacology of nivegacetor (RG6289), a potent and selective gamma secretase modulator in clinical development for the treatment of Alzheimer's disease
Lothar Lindemann, Julie Lambotte, Judith Rothe, et al.
British Journal of Clinical Pharmacology
|
October 11, 2018
A phase 1 healthy male volunteer single escalating dose study of the pharmacokinetics and pharmacodynamics of risdiplam (RG7916, RO7034067), a SMN2 splicing modifier
Stefan Sturm, Andreas Günther, Birgit Jaber, et al.
ACS Medicinal Chemistry Letters
|
June 20, 2020
Discovery of RO7185876, a Highly Potent γ-Secretase Modulator (GSM) as a Potential Treatment for Alzheimer's Disease
Hasane Ratni, Andre Alker, Bjoern Bartels, et al.
Journal of Medicinal Chemistry
|
January 18, 2020
Discovery of Balovaptan, a Vasopressin 1a Receptor Antagonist for the Treatment of Autism Spectrum Disorder
Patrick Schnider, Caterina Bissantz, Andreas Bruns, et al.
Human Molecular Genetics
|
August 9, 2021
SMN protein is required throughout life to prevent spinal muscular atrophy disease progression
Xin Zhao, Zhihua Feng, Nicole Risher, et al.
Human Molecular Genetics
|
March 3, 2016
Pharmacokinetics, pharmacodynamics, and efficacy of a small-molecule SMN2 splicing modifier in mouse models of spinal muscular atrophy
Xin Zhao, Zhihua Feng, Karen K Y Ling, et al.
Journal of Medicinal Chemistry
|
June 15, 2016
Specific Correction of Alternative Survival Motor Neuron 2 Splicing by Small Molecules: Discovery of a Potential Novel Medicine To Treat Spinal Muscular Atrophy
Hasane Ratni, Gary M Karp, Marla Weetall, et al.
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of 3