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Metabolites
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June 23, 2022
Impact of Nitisinone on the Cerebrospinal Fluid Metabolome of a Murine Model of Alkaptonuria
Andrew S Davison, Brendan P Norman, Hazel Sutherland, et al.
American Journal of Physiology. Cell Physiology
|
October 21, 2025
Dynamic time course of muscle proteome adaptation to programmed resistance training in rats
Connor A Stead, Stuart J Hesketh, Aaron C Q Thomas, et al.
JIMD Reports
|
May 6, 2015
Nitisinone Arrests but Does Not Reverse Ochronosis in Alkaptonuric Mice
Craig M Keenan, Andrew J Preston, Hazel Sutherland, et al.
Calcified Tissue International
|
October 15, 2020
Anatomical Distribution of Ochronotic Pigment in Alkaptonuric Mice is Associated with Calcified Cartilage Chondrocytes at Osteochondral Interfaces
Juliette H Hughes, Craig M Keenan, Hazel Sutherland, et al.
Annals of the Rheumatic Diseases
|
March 21, 2013
Ochronotic osteoarthropathy in a mouse model of alkaptonuria, and its inhibition by nitisinone
Andrew J Preston, Craig M Keenan, Hazel Sutherland, et al.
Human Molecular Genetics
|
May 25, 2026
Specific knockout of kidney homogentisate 1,2-dioxygenase reveals that local metabolism of tyrosine and homogentisic acid is negligible in alkaptonuria
Dominic A Rutland, Brendan P Norman, Juliette H Hughes, et al.
Clinical Chemistry
|
February 21, 2019
A Comprehensive LC-QTOF-MS Metabolic Phenotyping Strategy: Application to Alkaptonuria
Brendan P Norman, Andrew S Davison, Gordon A Ross, et al.
Journal of Inherited Metabolic Disease
|
September 11, 2019
Dietary restriction of tyrosine and phenylalanine lowers tyrosinemia associated with nitisinone therapy of alkaptonuria
Juliette H Hughes, Peter J M Wilson, Hazel Sutherland, et al.
Human Molecular Genetics
|
October 11, 2019
Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria
Juliette H Hughes, Ke Liu, Antonius Plagge, et al.
Metabolites
|
October 27, 2022
Comprehensive Biotransformation Analysis of Phenylalanine-Tyrosine Metabolism Reveals Alternative Routes of Metabolite Clearance in Nitisinone-Treated Alkaptonuria
Brendan P Norman, Andrew S Davison, Bryony Hickton, et al.
Page
of 4
Search research articles
Search
Showing results (21-30 of 35) with videos related to
Sort By:
Page
of 4
Metabolites
|
June 23, 2022
Impact of Nitisinone on the Cerebrospinal Fluid Metabolome of a Murine Model of Alkaptonuria
Andrew S Davison, Brendan P Norman, Hazel Sutherland, et al.
American Journal of Physiology. Cell Physiology
|
October 21, 2025
Dynamic time course of muscle proteome adaptation to programmed resistance training in rats
Connor A Stead, Stuart J Hesketh, Aaron C Q Thomas, et al.
JIMD Reports
|
May 6, 2015
Nitisinone Arrests but Does Not Reverse Ochronosis in Alkaptonuric Mice
Craig M Keenan, Andrew J Preston, Hazel Sutherland, et al.
Calcified Tissue International
|
October 15, 2020
Anatomical Distribution of Ochronotic Pigment in Alkaptonuric Mice is Associated with Calcified Cartilage Chondrocytes at Osteochondral Interfaces
Juliette H Hughes, Craig M Keenan, Hazel Sutherland, et al.
Annals of the Rheumatic Diseases
|
March 21, 2013
Ochronotic osteoarthropathy in a mouse model of alkaptonuria, and its inhibition by nitisinone
Andrew J Preston, Craig M Keenan, Hazel Sutherland, et al.
Human Molecular Genetics
|
May 25, 2026
Specific knockout of kidney homogentisate 1,2-dioxygenase reveals that local metabolism of tyrosine and homogentisic acid is negligible in alkaptonuria
Dominic A Rutland, Brendan P Norman, Juliette H Hughes, et al.
Clinical Chemistry
|
February 21, 2019
A Comprehensive LC-QTOF-MS Metabolic Phenotyping Strategy: Application to Alkaptonuria
Brendan P Norman, Andrew S Davison, Gordon A Ross, et al.
Journal of Inherited Metabolic Disease
|
September 11, 2019
Dietary restriction of tyrosine and phenylalanine lowers tyrosinemia associated with nitisinone therapy of alkaptonuria
Juliette H Hughes, Peter J M Wilson, Hazel Sutherland, et al.
Human Molecular Genetics
|
October 11, 2019
Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria
Juliette H Hughes, Ke Liu, Antonius Plagge, et al.
Metabolites
|
October 27, 2022
Comprehensive Biotransformation Analysis of Phenylalanine-Tyrosine Metabolism Reveals Alternative Routes of Metabolite Clearance in Nitisinone-Treated Alkaptonuria
Brendan P Norman, Andrew S Davison, Bryony Hickton, et al.
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of 4