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ACS Medicinal Chemistry Letters|January 22, 2026
S-adenosylhomocysteine analogs selectively suppress pan-coronavirus replication by inhibition of nsp14 methyltransferaseMonica Rosas-Lemus, Sudhakar Athe, George Minasov, et al.Signal Transduction and Targeted Therapy|November 18, 2025
Therapeutic targeting of endothelial calcium signaling accelerates the resolution of lung injuryWan Ching Chan, Man Long Kwok, Xinyan Qu, et al.Cell Reports. Medicine|October 5, 2023
End binding-3 inhibitor activates regenerative program in age-related macular degenerationQuinn Lee, Wan Ching Chan, Xinyan Qu, et al.Proceedings of the National Academy of Sciences of the United States of America|May 9, 2025
Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteineAnna E Maciag, Yue Yang, Alok K Sharma, et al.Cancer Research|December 19, 2024
A Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth and Induces Antitumor Immunity in Gastrointestinal CancerJeremy B Foote, Tyler E Mattox, Adam B Keeton, et al.Biorxiv : the Preprint Server for Biology|February 8, 2024
A Novel Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth in Mouse Models of GI CancerJeremy B Foote, Tyler E Mattox, Adam B Keeton, et al.Pageof 3