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Pharmacological Research|July 22, 2015
A novel quantitative assay of mitophagy: Combining high content fluorescence microscopy and mitochondrial DNA load to quantify mitophagy and identify novel pharmacological tools against pathogenic heteroplasmic mtDNAAlan Diot, Alex Hinks-Roberts, Tiffany Lodge, et al.
Aging Cell|December 14, 2020
Directly converted astrocytes retain the ageing features of the donor fibroblasts and elucidate the astrocytic contribution to human CNS health and diseaseNoemi Gatto, Cleide Dos Santos Souza, Allan C Shaw, et al.
Nature Communications|September 7, 2023
The master energy homeostasis regulator PGC-1α exhibits an mRNA nuclear export functionSimeon R Mihaylov, Lydia M Castelli, Ya-Hui Lin, et al.
Aging Cell|October 28, 2025
Telomerase Depletion Accelerates Ageing of the Zebrafish BrainRaquel R Martins, Savandara Besse, Pam S Ellis, et al.
Plos One|March 31, 2010
Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS)Laura E Cox, Laura Ferraiuolo, Emily F Goodall, et al.
Brain : a Journal of Neurology|October 25, 2019
C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosisScott P Allen, Benjamin Hall, Ryan Woof, et al.
Aging Biology|July 9, 2024
Aging, Parkinson's Disease, and Models: What Are the Challenges?Emily Rocha, Manish Chamoli, Shankar J Chinta, et al.
Annals of Neurology|September 13, 2013
TigarB causes mitochondrial dysfunction and neuronal loss in PINK1 deficiencyLaura J Flinn, Marcus Keatinge, Sandrine Bretaud, et al.
Progress in Neurobiology|February 15, 2020
Deep phenotyping of peripheral tissue facilitates mechanistic disease stratification in sporadic Parkinson's diseasePhillippa J Carling, Heather Mortiboys, Claire Green, et al.
Human Molecular Genetics|September 18, 2015
Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell deathMarcus Keatinge, Hai Bui, Aswin Menke, et al.
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