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ACS Infectious Diseases|July 9, 2026
2-Amino-3,4-Dihydroquinazolines Exhibit Potent Antimalarial Activity by Targeting Plasmepsin XMadeline G Dans, Jon Kyle Awalt, Nghi Nguyen, et al.
Nature Communications|May 27, 2023
Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparumKrittikorn Kümpornsin, Theerarat Kochakarn, Tomas Yeo, et al.
Cell Chemical Biology|March 24, 2023
Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasomeIoanna Deni, Barbara H Stokes, Kurt E Ward, et al.
Biorxiv : the Preprint Server for Biology|October 10, 2024
Identification of the drug/metabolite transporter 1 as a marker of quinine resistance in a NF54×Cam3.II P. falciparum genetic crossMariko Kanai, Sachel Mok, Tomas Yeo, et al.
The Journal of Clinical Investigation|March 28, 2025
Loss of GalNAc-T14 links O-glycosylation defects to alterations in B cell homing in IgA nephropathySindhuri Prakash, Nicholas J Steers, Yifu Li, et al.
Research Square|November 24, 2025
Collateral hypersensitivity between ZY19489 and piperaquine neutralizes PfCRT-mediated drug efflux and Plasmodium falciparum resistanceJohn Okombo, Tolla Ndiaye, Tarrick Qahash, et al.
Nature Communications|April 1, 2026
Collateral hypersensitivity between ZY19489 and piperaquine neutralizes PfCRT-mediated drug efflux and Plasmodium falciparum resistanceJohn Okombo, Tolla Ndiaye, Tarrick Qahash, et al.
Nature Microbiology|July 6, 2026
Identification of genetic markers of quinine partial resistance in Plasmodium falciparumMariko Kanai, Sachel Mok, Tomas Yeo, et al.
European Journal of Medicinal Chemistry|October 10, 2024
Exploration and characterization of the antimalarial activity of cyclopropyl carboxamides that target the mitochondrial protein, cytochrome bJon Kyle Awalt, Wenyin Su, William Nguyen, et al.
Science (New York, N.Y.)|November 28, 2024
Systematic in vitro evolution in Plasmodium falciparum reveals key determinants of drug resistanceMadeline R Luth, Karla P Godinez-Macias, Daisy Chen, et al.
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