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Molecular Cancer Therapeutics
|
May 2, 2006
Mode of action of the chloroethylating and carbamoylating moieties of the prodrug cloretazine
Kimiko Ishiguro, Helen A Seow, Philip G Penketh, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
June 21, 2005
1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[[1-(4-nitrophenyl)ethoxy]carbonyl]hydrazine: an anticancer agent targeting hypoxic cells
Helen A Seow, Philip G Penketh, Krishnamurthy Shyam, et al.
Oncology Research
|
January 18, 2006
The antineoplastic efficacy of the prodrug Cloretazine is produced by the synergistic interaction of carbamoylating and alkylating products of its activation
Raymond P Baumann, Helen A Seow, Krishnamurthy Shyam, et al.
Radiation Research
|
October 31, 2008
Generation of oxygen deficiency in cell culture using a two-enzyme system to evaluate agents targeting hypoxic tumor cells
Raymond P Baumann, Philip G Penketh, Helen A Seow, et al.
Leukemia Research
|
May 16, 2008
Lethality to leukemia cell lines of DNA interstrand cross-links generated by Cloretazine derived alkylating species
Philip G Penketh, Raymond P Baumann, Kimiko Ishiguro, et al.
The Journal of Biological Chemistry
|
May 25, 2004
Nuclear overexpression of NAD(P)H:quinone oxidoreductase 1 in Chinese hamster ovary cells increases the cytotoxicity of mitomycin C under aerobic and hypoxic conditions
Helen A Seow, Philip G Penketh, Michael F Belcourt, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 31, 2012
Design of a hypoxia-activated prodrug inhibitor of O6-alkylguanine-DNA alkyltransferase
Rui Zhu, Helen A Seow, Raymond P Baumann, et al.
Molecular Pharmacology
|
November 18, 2004
Nuclear localization of NADPH:cytochrome c (P450) reductase enhances the cytotoxicity of mitomycin C to Chinese hamster ovary cells
Helen A Seow, Michael F Belcourt, Philip G Penketh, et al.
International Journal of Radiation Biology
|
November 25, 2011
Preclinical evaluation of Laromustine for use in combination with radiation therapy in the treatment of solid tumors
Sara Rockwell, Yanfeng Liu, Helen A Seow, et al.
Autism Research : Official Journal of the International Society for Autism Research
|
March 17, 2023
Evaluation of clinical assessments of social abilities for use in autism clinical trials by the autism biomarkers consortium for clinical trials
Susan Faja, Maura Sabatos-DeVito, Aksheya Sridhar, et al.
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Search research articles
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Showing results (1-10 of 10) with videos related to
Sort By:
Page
of 1
Molecular Cancer Therapeutics
|
May 2, 2006
Mode of action of the chloroethylating and carbamoylating moieties of the prodrug cloretazine
Kimiko Ishiguro, Helen A Seow, Philip G Penketh, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
June 21, 2005
1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[[1-(4-nitrophenyl)ethoxy]carbonyl]hydrazine: an anticancer agent targeting hypoxic cells
Helen A Seow, Philip G Penketh, Krishnamurthy Shyam, et al.
Oncology Research
|
January 18, 2006
The antineoplastic efficacy of the prodrug Cloretazine is produced by the synergistic interaction of carbamoylating and alkylating products of its activation
Raymond P Baumann, Helen A Seow, Krishnamurthy Shyam, et al.
Radiation Research
|
October 31, 2008
Generation of oxygen deficiency in cell culture using a two-enzyme system to evaluate agents targeting hypoxic tumor cells
Raymond P Baumann, Philip G Penketh, Helen A Seow, et al.
Leukemia Research
|
May 16, 2008
Lethality to leukemia cell lines of DNA interstrand cross-links generated by Cloretazine derived alkylating species
Philip G Penketh, Raymond P Baumann, Kimiko Ishiguro, et al.
The Journal of Biological Chemistry
|
May 25, 2004
Nuclear overexpression of NAD(P)H:quinone oxidoreductase 1 in Chinese hamster ovary cells increases the cytotoxicity of mitomycin C under aerobic and hypoxic conditions
Helen A Seow, Philip G Penketh, Michael F Belcourt, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 31, 2012
Design of a hypoxia-activated prodrug inhibitor of O6-alkylguanine-DNA alkyltransferase
Rui Zhu, Helen A Seow, Raymond P Baumann, et al.
Molecular Pharmacology
|
November 18, 2004
Nuclear localization of NADPH:cytochrome c (P450) reductase enhances the cytotoxicity of mitomycin C to Chinese hamster ovary cells
Helen A Seow, Michael F Belcourt, Philip G Penketh, et al.
International Journal of Radiation Biology
|
November 25, 2011
Preclinical evaluation of Laromustine for use in combination with radiation therapy in the treatment of solid tumors
Sara Rockwell, Yanfeng Liu, Helen A Seow, et al.
Autism Research : Official Journal of the International Society for Autism Research
|
March 17, 2023
Evaluation of clinical assessments of social abilities for use in autism clinical trials by the autism biomarkers consortium for clinical trials
Susan Faja, Maura Sabatos-DeVito, Aksheya Sridhar, et al.
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of 1