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Cell Chemical Biology|September 6, 2025
A covalent inhibitor targeting Cys16 on RhoA in colorectal cancerTin-Yan Koo, Jason Ying Ki Li, Nga-Sze Lee, et al.Nature|March 20, 2025
The somatic mutation landscape of normal gastric epitheliumTim H H Coorens, Grace Collord, Hyungchul Jung, et al.Nature Communications|May 19, 2023
ADAR1-mediated RNA editing of SCD1 drives drug resistance and self-renewal in gastric cancerTin-Lok Wong, Jia-Jian Loh, Shixun Lu, et al.Gut|June 23, 2016
RNF43 germline and somatic mutation in serrated neoplasia pathway and its association with BRAF mutationHelen H N Yan, Jeffrey C W Lai, Siu Lun Ho, et al.Gut|November 21, 2024
Divergent lineage trajectories and genetic landscapes in human gastric intestinal metaplasia organoids associated with early neoplastic progressionSarah S K Yue, Yin Tong, Hoi Cheong Siu, et al.Gut|June 15, 2022
Escape from cell-cell and cell-matrix adhesion dependence underscores disease progression in gastric cancer organoid modelsYin Tong, Priscilla S W Cheng, Chung Sze Or, et al.Genome Medicine|November 1, 2022
Ganciclovir-induced mutations are present in a diverse spectrum of post-transplant malignanciesHu Fang, Helen H N Yan, Rebecca A Bilardi, et al.Nature Communications|May 17, 2022
Mutational landscape of normal epithelial cells in Lynch Syndrome patientsBernard C H Lee, Philip S Robinson, Tim H H Coorens, et al.Gut|March 29, 2020
Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profilesHelen H N Yan, Hoi Cheong Siu, Siu Lun Ho, et al.Cell Stem Cell|October 23, 2018
A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic ScreeningHelen H N Yan, Hoi Cheong Siu, Simon Law, et al.Pageof 4