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The Journal of Biological Chemistry|May 26, 2017
A dock and coalesce mechanism driven by hydrophobic interactions governs Cdc42 binding with its effector protein ACKGeorge J N Tetley, Helen R Mott, R Neil Cooley, et al.
Biochemical Society Transactions|July 1, 2021
Molecular subversion of Cdc42 signalling in cancerNatasha P Murphy, Ana Masara Binti Ahmad Mokhtar, Helen R Mott, et al.
Structure (London, England : 1993)|November 12, 2013
The structure of the RLIP76 RhoGAP-Ral binding domain dyad: fixed position of the domains leads to dual engagement of small G proteins at the membraneKarthik V Rajasekar, Louise J Campbell, Daniel Nietlispach, et al.
Biomolecular NMR Assignments|September 15, 2011
1H, 13C and 15N resonance assignments of the GTPase-activating (GAP) and Ral binding domains (GBD) of RLIP76 (RalBP1)Karthik V Rajasekar, Louise J Campbell, Daniel Nietlispach, et al.
Biochemistry|January 21, 2026
Cyclized Peptide Inhibitors of the Small G Protein Cdc42 Mimic Binding of Effector ProteinsNatasha P Murphy, George J N Tetley, Jefferson Revell, et al.
Biochemistry|October 17, 2013
Differential binding of RhoA, RhoB, and RhoC to protein kinase C-related kinase (PRK) isoforms PRK1, PRK2, and PRK3: PRKs have the highest affinity for RhoBCatherine L Hutchinson, Peter N Lowe, Stephen H McLaughlin, et al.
Biochemistry|March 1, 2011
Mutational analysis reveals a single binding interface between RhoA and its effector, PRK1Catherine L Hutchinson, Peter N Lowe, Stephen H McLaughlin, et al.
The Journal of Biological Chemistry|November 20, 2020
Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPasesCatherine A Hurd, Paul Brear, Jefferson Revell, et al.
Small Gtpases|May 17, 2023
ACKnowledging the role of the Activated-Cdc42 associated kinase (ACK) in regulating protein stability in cancerSamantha Hodder, Millie Fox, Ana Masara Binti Ahmad Mokhtar, et al.
The Journal of Biological Chemistry|August 15, 2018
Bond swapping from a charge cloud allows flexible coordination of upstream signals through WASP: Multiple regulatory roles for the WASP basic regionGeorge J N Tetley, Aydan Szeto, Adam J Fountain, et al.
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