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Helena Almqvist

Showing results (1-10 of 11) with videos related to

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Journal of Visualized Experiments : Jove|December 25, 2018
Using High Content Imaging to Quantify Target Engagement in Adherent CellsHanna Axelsson, Helena Almqvist, Brinton Seashore-Ludlow
Biochemistry|November 13, 2018
Quantitative Interpretation of Intracellular Drug Binding and Kinetics Using the Cellular Thermal Shift AssayBrinton Seashore-Ludlow, Hanna Axelsson, Helena Almqvist, et al.
Nature Protocols|August 8, 2014
The cellular thermal shift assay for evaluating drug target interactions in cellsRozbeh Jafari, Helena Almqvist, Hanna Axelsson, et al.
Bioorganic & Medicinal Chemistry|January 3, 2021
A FabG inhibitor targeting an allosteric binding site inhibits several orthologs from Gram-negative ESKAPE pathogensPeter Vella, Reshma Srilakshmi Rudraraju, Thomas Lundbäck, et al.
ACS Chemical Biology|February 14, 2018
In Situ Target Engagement Studies in Adherent CellsHanna Axelsson, Helena Almqvist, Magdalena Otrocka, et al.
Nature Communications|March 25, 2016
CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracilHelena Almqvist, Hanna Axelsson, Rozbeh Jafari, et al.
Journal of Biomolecular Screening|March 6, 2013
The use of TrkA-PathHunter assay in high-throughput screening to identify compounds that affect nerve growth factor signalingPontus Forsell, Helena Almqvist, Per Hillertz, et al.
Proceedings of the National Academy of Sciences of the United States of America|July 14, 2017
Prediction of intracellular exposure bridges the gap between target- and cell-based drug discoveryAndré Mateus, Laurie J Gordon, Gareth J Wayne, et al.
Journal of Medicinal Chemistry|July 6, 2016
Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosisKatharina Brunner, Selma Maric, Rudraraju Srilakshmi Reshma, et al.
Nature Communications|January 19, 2018
Targeted NUDT5 inhibitors block hormone signaling in breast cancer cellsBrent D G Page, Nicholas C K Valerie, Roni H G Wright, et al.
Pageof 2

Showing results (1-10 of 11) with videos related to

Sort By:
Pageof 2
Journal of Visualized Experiments : Jove|December 25, 2018
Using High Content Imaging to Quantify Target Engagement in Adherent CellsHanna Axelsson, Helena Almqvist, Brinton Seashore-Ludlow
Biochemistry|November 13, 2018
Quantitative Interpretation of Intracellular Drug Binding and Kinetics Using the Cellular Thermal Shift AssayBrinton Seashore-Ludlow, Hanna Axelsson, Helena Almqvist, et al.
Nature Protocols|August 8, 2014
The cellular thermal shift assay for evaluating drug target interactions in cellsRozbeh Jafari, Helena Almqvist, Hanna Axelsson, et al.
Bioorganic & Medicinal Chemistry|January 3, 2021
A FabG inhibitor targeting an allosteric binding site inhibits several orthologs from Gram-negative ESKAPE pathogensPeter Vella, Reshma Srilakshmi Rudraraju, Thomas Lundbäck, et al.
ACS Chemical Biology|February 14, 2018
In Situ Target Engagement Studies in Adherent CellsHanna Axelsson, Helena Almqvist, Magdalena Otrocka, et al.
Nature Communications|March 25, 2016
CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracilHelena Almqvist, Hanna Axelsson, Rozbeh Jafari, et al.
Journal of Biomolecular Screening|March 6, 2013
The use of TrkA-PathHunter assay in high-throughput screening to identify compounds that affect nerve growth factor signalingPontus Forsell, Helena Almqvist, Per Hillertz, et al.
Proceedings of the National Academy of Sciences of the United States of America|July 14, 2017
Prediction of intracellular exposure bridges the gap between target- and cell-based drug discoveryAndré Mateus, Laurie J Gordon, Gareth J Wayne, et al.
Journal of Medicinal Chemistry|July 6, 2016
Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosisKatharina Brunner, Selma Maric, Rudraraju Srilakshmi Reshma, et al.
Nature Communications|January 19, 2018
Targeted NUDT5 inhibitors block hormone signaling in breast cancer cellsBrent D G Page, Nicholas C K Valerie, Roni H G Wright, et al.
Pageof 2