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Biophysical Journal|February 27, 2026
In silico conformational dynamics of the α-actinin-2 actin-binding domain upon phosphorylationHelene Tigro, Matthew C Childers, Michael Regnier, et al.
ACS Omega|January 19, 2026
Desensitization of the Cardiac Troponin Complex by TnI Phosphorylation and Epigallocatechin-3-GallateHelene Tigro, Maria E Moutsoglou, Giho H Kim, et al.
The Journal of General Physiology|April 12, 2024
Myosin's powerstroke transitions define atomic scale movement of cardiac thin filament tropomyosinMichael J Rynkiewicz, Matthew C Childers, Olga E Karpicheva, et al.
Cells|January 8, 2025
FMR1 Disorders: Basics of Biology and Therapeutics in DevelopmentDrew A Gillett, Helene Tigro, Yuan Wang, et al.
Biorxiv : the Preprint Server for Biology|June 12, 2026
The hypertrophic cardiomyopathy mutation G768R makes cardiac myosin a high duty ratio motorDivya Pathak, Tugba N Ozturk, Aminah Dawood, et al.
Biorxiv : the Preprint Server for Biology|March 11, 2024
Hypertrophic cardiomyopathy mutations Y115H and E497D disrupt the folded-back state of human beta-cardiac myosin allostericallyNeha Nandwani, Debanjan Bhowmik, Matthew C Childers, et al.
Biophysical Journal|October 22, 2020
Edge Strand Dissociation and Conformational Changes in Transthyretin under Amyloidogenic ConditionsMatthew C Childers, Valerie Daggett
Protein Science : a Publication of the Protein Society|November 15, 2020
Conserved patterns and interactions in the unfolding transition state across SH3 domain structural homologuesCullen Demakis, Matthew C Childers, Valerie Daggett
Proceedings of the National Academy of Sciences of the United States of America|August 22, 2024
Multiscale modeling shows how 2'-deoxy-ATP rescues ventricular function in heart failureAbigail E Teitgen, Marcus T Hock, Kimberly J McCabe, et al.
Molecular and Cellular Neurosciences|March 19, 2023
Identification of cytoskeletal proteins as binding partners of Bri2 BRICHOS domainMakoto Shimozawa, Helene Tigro, Henrik Biverstål, et al.
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