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Journal of Molecular Biology|January 15, 2021
Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain VariantHelge M Magnussen, Danny T Huang
Seminars in Cell & Developmental Biology|January 8, 2022
Stress - Regulation of SUMO conjugation and of other Ubiquitin-Like ModifiersDragana Ilic, Helge M Magnussen, Marilyn Tirard
Frontiers in Molecular Neuroscience|August 3, 2023
An intellectual-disability-associated mutation of the transcriptional regulator NACC1 impairs glutamatergic neurotransmissionJames A Daniel, Sofia Elizarova, Ali H Shaib, et al.
The EMBO Journal|September 19, 2022
A non-canonical scaffold-type E3 ligase complex mediates protein UFMylationJoshua J Peter, Helge M Magnussen, Paul A DaRosa, et al.
Cell Reports|August 4, 2022
Human UFSP1 is an active protease that regulates UFM1 maturation and UFMylationDavid Millrine, Thomas Cummings, Stephen P Matthews, et al.
Genes & Development|December 18, 2020
Differential requirements for MDM2 E3 activity during embryogenesis and in adult miceTimothy J Humpton, Koji Nomura, Julia Weber, et al.
Nature|February 21, 2024
The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER transloconsLinda Makhlouf, Joshua J Peter, Helge M Magnussen, et al.
Nature Communications|May 1, 2020
Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domainHelge M Magnussen, Syed F Ahmed, Gary J Sibbet, et al.
EMBO Molecular Medicine|February 23, 2026
Encephalopathy-linked UFM1 variants impede neuronal protein translation, development, and functionCatarina Perdigão, Josefa Torres, Helge M Magnussen, et al.
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