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Hengmiao Cheng

Showing results (11-20 of 28) with videos related to

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ACS Medicinal Chemistry Letters|October 18, 2023
Structure-Based Design and Synthesis of Potent and Selective KRAS G12D InhibitorsHengmiao Cheng, Puhui Li, Ping Chen, et al.
Bioorganic & Medicinal Chemistry Letters|March 27, 2003
Azalide 3,6-ketals: antibacterial activity and structure-activity relationships of aryl and hetero aryl substituted analoguesSubas M Sakya, Peter Bertinato, Bryan Pratt, et al.
Bioorganic & Medicinal Chemistry Letters|November 28, 2006
5-Heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part III: molecular modeling studies on binding contribution of 1-(5-methylsulfonyl)pyrid-2-yl and 4-nitrileSubas M Sakya, Xinjun Hou, Martha L Minich, et al.
Bioorganic & Medicinal Chemistry Letters|August 6, 2002
Synthesis and SAR of azalide 3,6-ketal aromatic derivatives as potent Gram-positive and Gram-negative antibacterial agentsHengmiao Cheng, John P Dirlam, Carl B Ziegler, et al.
Bioorganic & Medicinal Chemistry|February 9, 2005
In vitro and in vivo profile of 2-(3-di-fluoromethyl-5-phenylpyrazol-1-yl)-5-methanesulfonylpyridine, a potent, selective, and orally active canine COX-2 inhibitorJin Li, Michael P Lynch, Kristin Lundy Demello, et al.
Bioorganic & Medicinal Chemistry Letters|September 10, 2002
Synthesis and activity of a novel class of tribasic macrocyclic antibiotics: the triamilidesMichael A Letavic, Brian S Bronk, Camilla D Bertsche, et al.
Bioorganic & Medicinal Chemistry Letters|April 6, 2010
The development and SAR of pyrrolidine carboxamide 11beta-HSD1 inhibitorsHengmiao Cheng, Jacqui Hoffman, Phuong Le, et al.
Molecular Cancer Therapeutics|July 14, 2011
PF-04691502, a potent and selective oral inhibitor of PI3K and mTOR kinases with antitumor activityJing Yuan, Pramod P Mehta, Min-Jean Yin, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug DesignHengmiao Cheng, Chunze Li, Simon Bailey, et al.
Journal of Medicinal Chemistry|August 29, 2012
Discovery of a novel class of exquisitely selective mesenchymal-epithelial transition factor (c-MET) protein kinase inhibitors and identification of the clinical candidate 2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol (PF-04217903) for the treatment of cancerJ Jean Cui, Michele McTigue, Mitchell Nambu, et al.
Pageof 3

Showing results (11-20 of 28) with videos related to

Sort By:
Pageof 3
ACS Medicinal Chemistry Letters|October 18, 2023
Structure-Based Design and Synthesis of Potent and Selective KRAS G12D InhibitorsHengmiao Cheng, Puhui Li, Ping Chen, et al.
Bioorganic & Medicinal Chemistry Letters|March 27, 2003
Azalide 3,6-ketals: antibacterial activity and structure-activity relationships of aryl and hetero aryl substituted analoguesSubas M Sakya, Peter Bertinato, Bryan Pratt, et al.
Bioorganic & Medicinal Chemistry Letters|November 28, 2006
5-Heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part III: molecular modeling studies on binding contribution of 1-(5-methylsulfonyl)pyrid-2-yl and 4-nitrileSubas M Sakya, Xinjun Hou, Martha L Minich, et al.
Bioorganic & Medicinal Chemistry Letters|August 6, 2002
Synthesis and SAR of azalide 3,6-ketal aromatic derivatives as potent Gram-positive and Gram-negative antibacterial agentsHengmiao Cheng, John P Dirlam, Carl B Ziegler, et al.
Bioorganic & Medicinal Chemistry|February 9, 2005
In vitro and in vivo profile of 2-(3-di-fluoromethyl-5-phenylpyrazol-1-yl)-5-methanesulfonylpyridine, a potent, selective, and orally active canine COX-2 inhibitorJin Li, Michael P Lynch, Kristin Lundy Demello, et al.
Bioorganic & Medicinal Chemistry Letters|September 10, 2002
Synthesis and activity of a novel class of tribasic macrocyclic antibiotics: the triamilidesMichael A Letavic, Brian S Bronk, Camilla D Bertsche, et al.
Bioorganic & Medicinal Chemistry Letters|April 6, 2010
The development and SAR of pyrrolidine carboxamide 11beta-HSD1 inhibitorsHengmiao Cheng, Jacqui Hoffman, Phuong Le, et al.
Molecular Cancer Therapeutics|July 14, 2011
PF-04691502, a potent and selective oral inhibitor of PI3K and mTOR kinases with antitumor activityJing Yuan, Pramod P Mehta, Min-Jean Yin, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug DesignHengmiao Cheng, Chunze Li, Simon Bailey, et al.
Journal of Medicinal Chemistry|August 29, 2012
Discovery of a novel class of exquisitely selective mesenchymal-epithelial transition factor (c-MET) protein kinase inhibitors and identification of the clinical candidate 2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol (PF-04217903) for the treatment of cancerJ Jean Cui, Michele McTigue, Mitchell Nambu, et al.
Pageof 3