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Chimia
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December 2, 2014
Adventures in drug-like chemistry space: from oxetanes to spiroazetidines and beyond!
Mark Rogers-Evans, Henner Knust, Jean-Marc Plancher, et al.
Neuropharmacology
|
August 10, 2014
Mapping the binding pocket of a novel, high-affinity, slow dissociating tachykinin NK3 receptor antagonist: biochemical and electrophysiological characterization
Pari Malherbe, Frédéric Knoflach, Anne Marcuz, et al.
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|
October 4, 2017
Preclinical Evaluation of <sup>18</sup>F-RO6958948, <sup>11</sup>C-RO6931643, and <sup>11</sup>C-RO6924963 as Novel PET Radiotracers for Imaging Tau Aggregates in Alzheimer Disease
Michael Honer, Luca Gobbi, Henner Knust, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 11, 2009
Imidazo[1,5-a][1,2,4]-triazolo[1,5-d][1,4]benzodiazepines as potent and highly selective GABAA alpha5 inverse agonists with potential for the treatment of cognitive dysfunction
Bernd Buettelmann, Theresa M Ballard, Rodolfo Gasser, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 21, 2010
Rational design of novel pyrrolidine derivatives as orally active neurokinin-3 receptor antagonists
Hassen Ratni, Theresa M Ballard, Caterina Bissantz, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 19, 2009
The discovery and unique pharmacological profile of RO4938581 and RO4882224 as potent and selective GABAA alpha5 inverse agonists for the treatment of cognitive dysfunction
Henner Knust, Guido Achermann, Theresa Ballard, et al.
Psychopharmacology
|
October 22, 2008
RO4938581, a novel cognitive enhancer acting at GABAA alpha5 subunit-containing receptors
Theresa M Ballard, Frédéric Knoflach, Eric Prinssen, et al.
Journal of Medicinal Chemistry
|
August 24, 2012
Bis(arylvinyl)pyrazines, -pyrimidines, and -pyridazines as imaging agents for tau fibrils and β-amyloid plaques in Alzheimer's disease models
Alexander Boländer, Daniel Kieser, Constantin Voss, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 4, 2009
Discovery of the imidazo[1,5-a][1,2,4]-triazolo[1,5-d][1,4]benzodiazepine scaffold as a novel, potent and selective GABA(A) alpha5 inverse agonist series
Guido Achermann, Theresa M Ballard, Francesca Blasco, et al.
Scientific Reports
|
April 9, 2021
Basmisanil, a highly selective GABA<sub>A</sub>-α5 negative allosteric modulator: preclinical pharmacology and demonstration of functional target engagement in man
Joerg F Hipp, Frederic Knoflach, Robert Comley, et al.
Page
of 3
Search research articles
Search
Showing results (11-20 of 22) with videos related to
Sort By:
Page
of 3
Chimia
|
December 2, 2014
Adventures in drug-like chemistry space: from oxetanes to spiroazetidines and beyond!
Mark Rogers-Evans, Henner Knust, Jean-Marc Plancher, et al.
Neuropharmacology
|
August 10, 2014
Mapping the binding pocket of a novel, high-affinity, slow dissociating tachykinin NK3 receptor antagonist: biochemical and electrophysiological characterization
Pari Malherbe, Frédéric Knoflach, Anne Marcuz, et al.
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|
October 4, 2017
Preclinical Evaluation of <sup>18</sup>F-RO6958948, <sup>11</sup>C-RO6931643, and <sup>11</sup>C-RO6924963 as Novel PET Radiotracers for Imaging Tau Aggregates in Alzheimer Disease
Michael Honer, Luca Gobbi, Henner Knust, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 11, 2009
Imidazo[1,5-a][1,2,4]-triazolo[1,5-d][1,4]benzodiazepines as potent and highly selective GABAA alpha5 inverse agonists with potential for the treatment of cognitive dysfunction
Bernd Buettelmann, Theresa M Ballard, Rodolfo Gasser, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 21, 2010
Rational design of novel pyrrolidine derivatives as orally active neurokinin-3 receptor antagonists
Hassen Ratni, Theresa M Ballard, Caterina Bissantz, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 19, 2009
The discovery and unique pharmacological profile of RO4938581 and RO4882224 as potent and selective GABAA alpha5 inverse agonists for the treatment of cognitive dysfunction
Henner Knust, Guido Achermann, Theresa Ballard, et al.
Psychopharmacology
|
October 22, 2008
RO4938581, a novel cognitive enhancer acting at GABAA alpha5 subunit-containing receptors
Theresa M Ballard, Frédéric Knoflach, Eric Prinssen, et al.
Journal of Medicinal Chemistry
|
August 24, 2012
Bis(arylvinyl)pyrazines, -pyrimidines, and -pyridazines as imaging agents for tau fibrils and β-amyloid plaques in Alzheimer's disease models
Alexander Boländer, Daniel Kieser, Constantin Voss, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 4, 2009
Discovery of the imidazo[1,5-a][1,2,4]-triazolo[1,5-d][1,4]benzodiazepine scaffold as a novel, potent and selective GABA(A) alpha5 inverse agonist series
Guido Achermann, Theresa M Ballard, Francesca Blasco, et al.
Scientific Reports
|
April 9, 2021
Basmisanil, a highly selective GABA<sub>A</sub>-α5 negative allosteric modulator: preclinical pharmacology and demonstration of functional target engagement in man
Joerg F Hipp, Frederic Knoflach, Robert Comley, et al.
Page
of 3