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Handbook of Experimental Pharmacology|June 26, 2019
Potential of Intestine-Selective FXR Modulation for Treatment of Metabolic DiseaseTim van Zutphen, Anna Bertolini, Hilde D de Vries, et al.Pediatric Research|October 2, 2024
Elevated plasma bile acids coincide with cardiac stress and inflammation in young Cyp2c70-/- miceHilde D de Vries, Tim R Eijgenraam, Vincent W Bloks, et al.Clinical Science (London, England : 1979)|November 1, 2023
Gut microbiota depletion aggravates bile acid-induced liver pathology in mice with a human-like bile acid compositionEsther Verkade, Wenqiang Shen, Milaine V Hovingh, et al.Pediatric Research|September 23, 2022
Perinatal exposure to UDCA prevents neonatal cholestasis in Cyp2c70-/- mice with human-like bile acidsHilde D de Vries, Anna Palmiotti, Rumei Li, et al.Journal of Lipid Research|September 12, 2019
A human-like bile acid pool induced by deletion of hepatic Cyp2c70 modulates effects of FXR activation in miceJan Freark de Boer, Esther Verkade, Niels L Mulder, et al.Journal of Lipid Research|October 9, 2021
Low production of 12α-hydroxylated bile acids prevents hepatic steatosis in Cyp2c70-/- mice by reducing fat absorptionRumei Li, Anna Palmiotti, Hilde D de Vries, et al.Biomedicines|September 28, 2023
Bile Acid Sequestration via Colesevelam Reduces Bile Acid Hydrophobicity and Improves Liver Pathology in Cyp2c70-/- Mice with a Human-like Bile Acid CompositionAnna Palmiotti, Hilde D de Vries, Milaine V Hovingh, et al.Liver International : Official Journal of the International Association for the Study of the Liver|April 9, 2026
Farnesoid x Receptor Deficiency Promotes Hepatocytic Injury in Cyp2c70-Deficient Mice With a Human-Like Bile Acid CompositionHilde D de Vries, Jinxiao Li, Kirill Ustyantsev, et al.Journal of Lipid Research|June 25, 2026
Mice with humanized FXR ligand-binding domain display distinct metabolic responses upon pharmacological FXR stimulationJinxiao Li, Hilde D de Vries, Kirill Ustyantsev, et al.Cellular and Molecular Gastroenterology and Hepatology|April 10, 2026
Bile acid detergency as determinant of liver pathology in a humanized mouse model of progressive familial intrahepatic cholestasis type 3Lixin Ke, Niels L Mulder, Milaine V Hovingh, et al.Pageof 2