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Bioorganic & Medicinal Chemistry|June 11, 2011
Discovery of 4-[4-({(3R)-1-butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]benzoic acid hydrochloride: a highly potent orally available CCR5 selective antagonistRena Nishizawa, Toshihiko Nishiyama, Katsuya Hisaichi, et al.
Journal of Medicinal Chemistry|September 16, 2021
Indole Chloropyridinyl Ester-Derived SARS-CoV-2 3CLpro Inhibitors: Enzyme Inhibition, Antiviral Efficacy, Structure-Activity Relationship, and X-ray Structural StudiesArun K Ghosh, Jakka Raghavaiah, Dana Shahabi, et al.
Neurobiology of Disease|September 3, 2005
Increase of C1q biosynthesis in brain microglia and macrophages during lentivirus infection in the rhesus macaque is sensitive to antiretroviral treatment with 6-chloro-2',3'-dideoxyguanosineCandan Depboylu, Martin K-H Schäfer, Wilhelm J Schwaeble, et al.
Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis|January 7, 2023
Preserved SARS-CoV-2 neutralizing IgG activity of in-house manufactured COVID-19 convalescent plasmaMakoto Inada, Tomiteru Togano, Mari Terada, et al.
Antimicrobial Agents and Chemotherapy|February 14, 2013
GRL-0519, a novel oxatricyclic ligand-containing nonpeptidic HIV-1 protease inhibitor (PI), potently suppresses replication of a wide spectrum of multi-PI-resistant HIV-1 variants in vitroMasayuki Amano, Yasushi Tojo, Pedro Miguel Salcedo-Gómez, et al.
Oncotarget|September 9, 2017
Restoration of immune surface molecules in Kaposi sarcoma-associated herpes virus infected cells by lenalidomide and pomalidomideDavid A Davis, Suraj Mishra, Holda A Anagho, et al.
Antimicrobial Agents and Chemotherapy|September 14, 2016
A Modified P1 Moiety Enhances In Vitro Antiviral Activity against Various Multidrug-Resistant HIV-1 Variants and In Vitro Central Nervous System Penetration Properties of a Novel Nonpeptidic Protease Inhibitor, GRL-10413Masayuki Amano, Pedro Miguel Salcedo-Gómez, Rui Zhao, et al.
Organic & Biomolecular Chemistry|October 15, 2015
Design, synthesis, biological evaluation and X-ray structural studies of HIV-1 protease inhibitors containing substituted fused-tetrahydropyranyl tetrahydrofuran as P2-ligandsArun K Ghosh, Cuthbert D Martyr, Luke A Kassekert, et al.
RSC Medicinal Chemistry|June 30, 2026
Design, synthesis, and X-ray structural studies of potent SARS-CoV-2 Mpro inhibitors containing tetrahydroisoquinoline-3-carboxamides as P2 ligandsArun K Ghosh, Ashish Sharma, Satyanarayana Iddum, et al.
Chemmedchem|October 23, 2014
Design of gem-difluoro-bis-tetrahydrofuran as P2 ligand for HIV-1 protease inhibitors to improve brain penetration: synthesis, X-ray studies, and biological evaluationArun K Ghosh, Sofiya Yashchuk, Akira Mizuno, et al.
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