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Oncoimmunology|November 20, 2012
TLR3/TICAM-1 signaling in tumor cell RIP3-dependent necroptosisTsukasa Seya, Hiroaki Shime, Hiromi Takaki, et al.
Biochemical and Biophysical Research Communications|January 18, 2015
Pam2 lipopeptides systemically increase myeloid-derived suppressor cells through TLR2 signalingAkira Maruyama, Hiroaki Shime, Yohei Takeda, et al.
Cancer Science|September 24, 2015
Adjuvant for vaccine immunotherapy of cancer--focusing on Toll-like receptor 2 and 3 agonists for safely enhancing antitumor immunityTsukasa Seya, Hiroaki Shime, Yohei Takeda, et al.
Oncoimmunology|January 4, 2018
Toll-like receptor 2 ligand and interferon-γ suppress anti-tumor T cell responses by enhancing the immunosuppressive activity of monocytic myeloid-derived suppressor cellsHiroaki Shime, Akira Maruyama, Sumito Yoshida, et al.
Frontiers in Immunology|March 30, 2018
Type I Interferon-Independent Dendritic Cell Priming and Antitumor T Cell Activation Induced by a Mycoplasma fermentans LipopeptideYohei Takeda, Masahiro Azuma, Kenji Funami, et al.
Cancer Science|May 29, 2010
Adjuvant engineering for cancer immunotherapy: Development of a synthetic TLR2 ligand with increased cell adhesionTakashi Akazawa, Norimitsu Inoue, Hiroaki Shime, et al.
Microbiology and Immunology|April 27, 2011
Development of monoclonal antibodies that specifically interact with necrotic lymphoma cellsKentaro Wakasa, Hiroaki Shime, Mitsue Kurita-Taniguchi, et al.
Journal of Innate Immunity|November 7, 2013
Myeloid-derived suppressor cells confer tumor-suppressive functions on natural killer cells via polyinosinic:polycytidylic acid treatment in mouse tumor modelsHiroaki Shime, Ayako Kojima, Akira Maruyama, et al.
Cancer Science|March 3, 2016
Live imaging of transforming growth factor-β activated kinase 1 activation in Lewis lung carcinoma 3LL cells implanted into syngeneic mice and treated with polyinosinic:polycytidylic acidSaori Takaoka, Yuji Kamioka, Kanako Takakura, et al.
Plos One|January 24, 2017
The Anti-Oxidant Ergothioneine Augments the Immunomodulatory Function of TLR Agonists by Direct Action on MacrophagesSumito Yoshida, Hiroaki Shime, Kenji Funami, et al.
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