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Advances in Pharmacology (San Diego, Calif.)|August 11, 2022
Cytochrome P450s in chimeric mice with humanized liverShotaro Uehara, Hiroshi Suemizu, Hiroshi Yamazaki
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|November 14, 2019
A novel Css-MRTpo approach to simulate oral plasma concentration-time profiles of the partial glucokinase activator PF-04937319 and its disproportionate N-demethylated metabolite in humans using chimeric mice with humanized liversHidetaka Kamimura, Shotaro Uehara, Hiroshi Suemizu
Drug Metabolism and Pharmacokinetics|January 29, 2021
In vivo drug interactions of itopride and trimethylamine mediated by flavin-containing monooxygenase 3 in humanized-liver miceMakiko Shimizu, Shotaro Uehara, Hiroshi Suemizu, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|January 1, 2019
Regioselective hydroxylation of an antiarrhythmic drug, propafenone, mediated by rat liver cytochrome P450 2D2 differs from that catalyzed by human P450 2D6Shotaro Uehara, Norie Murayama, Hiroshi Yamazaki, et al.
Drug Metabolism and Pharmacokinetics|April 9, 2023
Roles of human cytochrome P450 3A4/5 in dexamethasone 6β-hydroxylation mediated by liver microsomes and humanized liver in chimeric mice metabolically suppressed with azamulinShotaro Uehara, Makiko Shimizu, Hiroshi Suemizu, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|November 8, 2023
Empirical scaling factor for predicting human pharmacokinetic profiles of disproportionate metabolites using the Css-MRTpo method and chimeric mice with humanised liversHidetaka Kamimura, Shotaro Uehara, Nao Yoneda, et al.
The Journal of Veterinary Medical Science|October 11, 2012
Application of a new convenience gender sorting method for mouse spermatozoa to mouse reproductive engineering technologyHaruo Hashimoto, Tomoo Eto, Hiroshi Suemizu, et al.
Regulatory Toxicology and Pharmacology : RTP|August 27, 2014
Pharmacokinetics and effects on serum cholinesterase activities of organophosphorus pesticides acephate and chlorpyrifos in chimeric mice transplanted with human hepatocytesHiroshi Suemizu, Shigeto Sota, Miyuki Kuronuma, et al.
Drug Metabolism and Pharmacokinetics|October 8, 2021
Oxidative metabolism and pharmacokinetics of the EGFR inhibitor BIBX1382 in chimeric NOG-TKm30 mice transplanted with human hepatocytesShotaro Uehara, Nao Yoneda, Yuichiro Higuchi, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 3, 2020
Human Aldehyde Oxidase 1-Mediated Carbazeran Oxidation in Chimeric TK-NOG Mice Transplanted with Human HepatocytesShotaro Uehara, Nao Yoneda, Yuichiro Higuchi, et al.
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