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Neurochemistry International|August 30, 2012
Structural insight into receptor-selectivity for lurasidoneOsamu Ichikawa, Kazuhiko Okazaki, Hiroyuki Nakahira, et al.
Bioorganic & Medicinal Chemistry Letters|November 16, 2010
Discovery of new chemotype dipeptidyl peptidase IV inhibitors having (R)-3-amino-3-methyl piperidine as a pharmacophoreYukihiro Nishio, Hidenori Kimura, Shinya Tosaki, et al.
Bioorganic & Medicinal Chemistry|September 4, 2012
Discovery of 3H-imidazo[4,5-c]quinolin-4(5H)-ones as potent and selective dipeptidyl peptidase IV (DPP-4) inhibitorsYohei Ikuma, Hitoshi Hochigai, Hidenori Kimura, et al.
Bioorganic & Medicinal Chemistry|January 18, 2015
Discovery of 3H-imidazo[4,5-c]quinolin-4(5H)-ones as potent and selective dipeptidyl peptidase IV (DPP-4) inhibitors: use of a carboxylate prodrug to improve bioavailabilityYohei Ikuma, Hitoshi Hochigai, Hidenori Kimura, et al.
Bioorganic & Medicinal Chemistry|August 26, 2011
2-({6-[(3R)-3-amino-3-methylpiperidine-1-yl]-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-5H-pyrrolo[3,2-d]pyrimidine-5-yl}methyl)-4-fluorobenzonitrile (DSR-12727): a potent, orally active dipeptidyl peptidase IV inhibitor without mechanism-based inactivation of CYP3AYukihiro Nishio, Hidenori Kimura, Naoyuki Sawada, et al.
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