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Biomacromolecules|March 21, 2019
Oligoarginine-Bearing Tandem Repeat Penetration-Accelerating Sequence Delivers Protein to Cytosol via Caveolae-Mediated EndocytosisAkiko Okuda, Shinya Tahara, Hisaaki Hirose, et al.Chemical Communications (Cambridge, England)|October 6, 2012
Transformation of an antimicrobial peptide into a plasma membrane-permeable, mitochondria-targeted peptide via the substitution of lysine with arginineIkuhiko Nakase, Shinya Okumura, Sayaka Katayama, et al.Angewandte Chemie (International Ed. in English)|June 11, 2021
Liquid Droplet Formation and Facile Cytosolic Translocation of IgG in the Presence of Attenuated Cationic Amphiphilic Lytic PeptidesTakahiro Iwata, Hisaaki Hirose, Kentarou Sakamoto, et al.Molecular Therapy : the Journal of the American Society of Gene Therapy|February 16, 2012
Transient focal membrane deformation induced by arginine-rich peptides leads to their direct penetration into cellsHisaaki Hirose, Toshihide Takeuchi, Hiroko Osakada, et al.Journal of the American Chemical Society|June 18, 2013
Dynamic amphiphile libraries to screen for the "fragrant" delivery of siRNA into HeLa cells and human primary fibroblastsCharlotte Gehin, Javier Montenegro, Eun-Kyoung Bang, et al.Scientific Reports|April 16, 2022
Piezo1 activation using Yoda1 inhibits macropinocytosis in A431 human epidermoid carcinoma cellsMasashi Kuriyama, Hisaaki Hirose, Toshihiro Masuda, et al.Biomaterials|August 5, 2025
SARS-CoV-2 inhibition through mRNA delivery using engineered extracellular vesicles displaying the spike proteinYuna Nakagawa, Yoshimasa Kawaguchi, Hisaaki Hirose, et al.Bioconjugate Chemistry|November 5, 2024
Polysaccharide-Based Coacervate Microgel Bearing Cationic Peptides That Achieve Dynamic Cell-Membrane Structure Alteration and Facile Cytosolic Infusion of IgGsJunya Michibata, Yoshimasa Kawaguchi, Hisaaki Hirose, et al.ACS Chemical Biology|July 10, 2013
Curvature engineering: positive membrane curvature induced by epsin N-terminal peptide boosts internalization of octaarginineSílvia Pujals, Hiroki Miyamae, Sergii Afonin, et al.Bioorganic & Medicinal Chemistry Letters|April 23, 2020
Enhancing the activity of membrane remodeling epsin-peptide by trimerizationWei-Yuan Hsu, Toshihiro Masuda, Sergii Afonin, et al.Pageof 5