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Nature Medicine|October 7, 2008
Glutaminyl cyclase inhibition attenuates pyroglutamate Abeta and Alzheimer's disease-like pathologyStephan Schilling, Ulrike Zeitschel, Torsten Hoffmann, et al.European Journal of Medicinal Chemistry|August 6, 2019
Novel reverse thia-analogs of fosmidomycin: Synthesis and antiplasmodial activityClaudia Lienau, Tobias Gräwert, Leandro A Alves Avelar, et al.The American Journal of Pathology|June 11, 2013
Pyroglutamate-3 amyloid-β deposition in the brains of humans, non-human primates, canines, and Alzheimer disease-like transgenic mouse modelsJeffrey L Frost, Kevin X Le, Holger Cynis, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|September 9, 2011
Selective hippocampal neurodegeneration in transgenic mice expressing small amounts of truncated Aβ is induced by pyroglutamate-Aβ formationAnca Alexandru, Wolfgang Jagla, Sigrid Graubner, et al.Alzheimer'S Research & Therapy|January 14, 2023
A novel human tau knock-in mouse model reveals interaction of Abeta and human tau under progressing cerebral amyloidosis in 5xFAD miceSusan Barendrecht, An Schreurs, Stefanie Geissler, et al.Biological Chemistry|September 10, 2015
IsoQC (QPCTL) knock-out mice suggest differential substrate conversion by glutaminyl cyclase isoenzymesAndreas Becker, Rico Eichentopf, Reinhard Sedlmeier, et al.Advanced Science (Weinheim, Baden-Wurttemberg, Germany)|March 2, 2024
Consequences of Amyloid-β Deficiency for the LiverGayane Hrachia Buniatian, Ute Schwinghammer, Roman Tremmel, et al.Cells|February 25, 2020
Antifibrotic Effects of Amyloid-Beta and Its Loss in Cirrhotic LiverGayane Hrachia Buniatian, Ralf Weiskirchen, Thomas S Weiss, et al.Nature Neuroscience|November 17, 2020
Acute targeting of pre-amyloid seeds in transgenic mice reduces Alzheimer-like pathology later in lifeRuth E Uhlmann, Christine Rother, Jay Rasmussen, et al.Antiviral Research|September 21, 2024
Orally bioavailable RORγ/DHODH dual host-targeting small molecules with broad-spectrum antiviral activityAlexandra Herrmann, Christian Gege, Christina Wangen, et al.Pageof 6