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Holger Fischer

Showing results (21-30 of 61) with videos related to

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Journal of Medicinal Chemistry|April 27, 2012
Cytotoxic effects of combination of oxidosqualene cyclase inhibitors with atorvastatin in human cancer cellsDavide Staedler, Catherine Chapuis-Bernasconi, Henrietta Dehmlow, et al.
Molecular Pharmaceutics|November 13, 2015
Estimation of Drug Binding to Brain Tissue: Methodology and in Vivo Application of a Distribution Assay in Brain Polar LipidsSara Belli, Frauke Assmus, Bjoern Wagner, et al.
Journal of Medicinal Chemistry|November 30, 2011
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data setsHolger Fischer, Elke-Astrid Atzpodien, Miklos Csato, et al.
Bioorganic & Medicinal Chemistry Letters|September 23, 2008
Design, synthesis and structure-activity relationship of simple bis-amides as potent inhibitors of GlyT1Synèse Jolidon, Daniela Alberati, Adam Dowle, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|January 17, 2021
Multiorgan Crystal Deposition of an Amphoteric Drug in Rats Due to Lysosomal Accumulation and Conversion to a Poorly Soluble Hydrochloride SaltBarbara Lenz, Andreas Brink, Michael J Mihatsch, et al.
Journal of Medicinal Chemistry|March 31, 2010
Oxetanes in drug discovery: structural and synthetic insightsGeorg Wuitschik, Erick M Carreira, Björn Wagner, et al.
Chemmedchem|September 16, 2016
Effect of Partially Fluorinated N-Alkyl-Substituted Piperidine-2-carboxamides on Pharmacologically Relevant PropertiesRaffael Vorberg, Nils Trapp, Daniel Zimmerli, et al.
Journal of Medicinal Chemistry|June 14, 2017
In Silico Absorption, Distribution, Metabolism, Excretion, and Pharmacokinetics (ADME-PK): Utility and Best Practices. An Industry Perspective from the International Consortium for Innovation through Quality in Pharmaceutical DevelopmentFranco Lombardo, Prashant V Desai, Rieko Arimoto, et al.
Journal of Medicinal Chemistry|November 3, 2015
Fluorination Patterning: A Study of Structural Motifs That Impact Physicochemical Properties of Relevance to Drug DiscoveryQuentin A Huchet, Bernd Kuhn, Björn Wagner, et al.
Journal of Medicinal Chemistry|February 6, 2015
Discovery of highly selective brain-penetrant vasopressin 1a antagonists for the potential treatment of autism via a chemogenomic and scaffold hopping approachHasane Ratni, Mark Rogers-Evans, Caterina Bissantz, et al.
Pageof 7

Showing results (21-30 of 61) with videos related to

Sort By:
Pageof 7
Journal of Medicinal Chemistry|April 27, 2012
Cytotoxic effects of combination of oxidosqualene cyclase inhibitors with atorvastatin in human cancer cellsDavide Staedler, Catherine Chapuis-Bernasconi, Henrietta Dehmlow, et al.
Molecular Pharmaceutics|November 13, 2015
Estimation of Drug Binding to Brain Tissue: Methodology and in Vivo Application of a Distribution Assay in Brain Polar LipidsSara Belli, Frauke Assmus, Bjoern Wagner, et al.
Journal of Medicinal Chemistry|November 30, 2011
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data setsHolger Fischer, Elke-Astrid Atzpodien, Miklos Csato, et al.
Bioorganic & Medicinal Chemistry Letters|September 23, 2008
Design, synthesis and structure-activity relationship of simple bis-amides as potent inhibitors of GlyT1Synèse Jolidon, Daniela Alberati, Adam Dowle, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|January 17, 2021
Multiorgan Crystal Deposition of an Amphoteric Drug in Rats Due to Lysosomal Accumulation and Conversion to a Poorly Soluble Hydrochloride SaltBarbara Lenz, Andreas Brink, Michael J Mihatsch, et al.
Journal of Medicinal Chemistry|March 31, 2010
Oxetanes in drug discovery: structural and synthetic insightsGeorg Wuitschik, Erick M Carreira, Björn Wagner, et al.
Chemmedchem|September 16, 2016
Effect of Partially Fluorinated N-Alkyl-Substituted Piperidine-2-carboxamides on Pharmacologically Relevant PropertiesRaffael Vorberg, Nils Trapp, Daniel Zimmerli, et al.
Journal of Medicinal Chemistry|June 14, 2017
In Silico Absorption, Distribution, Metabolism, Excretion, and Pharmacokinetics (ADME-PK): Utility and Best Practices. An Industry Perspective from the International Consortium for Innovation through Quality in Pharmaceutical DevelopmentFranco Lombardo, Prashant V Desai, Rieko Arimoto, et al.
Journal of Medicinal Chemistry|November 3, 2015
Fluorination Patterning: A Study of Structural Motifs That Impact Physicochemical Properties of Relevance to Drug DiscoveryQuentin A Huchet, Bernd Kuhn, Björn Wagner, et al.
Journal of Medicinal Chemistry|February 6, 2015
Discovery of highly selective brain-penetrant vasopressin 1a antagonists for the potential treatment of autism via a chemogenomic and scaffold hopping approachHasane Ratni, Mark Rogers-Evans, Caterina Bissantz, et al.
Pageof 7