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Frontiers in Pharmacology|October 23, 2024
T-cell engagers: model interrogation as a tool to quantify the interplay of relative affinity and target expression on trimer formationMassimo Lai, Cesar Pichardo-Almarza, Meghna Verma, et al.
Clinical Pharmacokinetics|August 30, 2014
Population pharmacokinetics of rabeprazole and dosing recommendations for the treatment of gastroesophageal reflux disease in children aged 1-11 yearsSarah C McLeay, Bruce Green, William Treem, et al.
CPT: Pharmacometrics & Systems Pharmacology|November 11, 2023
A tutorial for model-based evaluation and translation of cardiovascular safety in preclinical trialsVictoria Kulesh, Igor Vasyutin, Alina Volkova, et al.
Journal of Pharmacokinetics and Pharmacodynamics|January 25, 2012
Population pharmacodynamic modeling of various extended-release formulations of methylphenidate in children with attention deficit hyperactivity disorder via meta-analysisHolly Kimko, Ekaterina Gibiansky, Leonid Gibiansky, et al.
Drug Discovery Today|February 4, 2026
Digital twins for accelerating drug discovery and development: opportunities and challengesSai Phanindra Venkatapurapu, Lindsay Clegg, Andrzej Nowojewski, et al.
Clinical Pharmacology in Drug Development|December 1, 2018
Toward Dynamic Prescribing Information: Codevelopment of Companion Model-Informed Precision Dosing Tools in Drug DevelopmentThomas M Polasek, Craig R Rayner, Richard W Peck, et al.
Plos Computational Biology|July 22, 2022
Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology modelAlvaro Ruiz-Martinez, Chang Gong, Hanwen Wang, et al.
CPT: Pharmacometrics & Systems Pharmacology|May 14, 2025
An Integrative Mechanistic Model of Type 1 IFN-Mediated Inflammation in Systemic Lupus ErythematosusAlina Volkova, Victor Sokolov, Florencia Tettamanti, et al.
Journal of Pharmaceutical Sciences|October 28, 2023
Physiological Indirect Response Model to Omics-Powered Quantitative Systems Pharmacology ModelAydar Uatay, Louis Gall, Linda Irons, et al.
Journal of Pharmacokinetics and Pharmacodynamics|August 21, 2015
Modeling population heterogeneity in viral dynamics for chronic hepatitis C infection: Insights from Phase 3 telaprevir clinical studiesEric L Haseltine, Holly Kimko, Haobin Luo, et al.
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