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The Journal of Pharmacology and Experimental Therapeutics|May 26, 2004
Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: prominent roles for CYP3A and CYP2D6Zeruesenay Desta, Bryan A Ward, Nadia V Soukhova, et al.Cancer Chemotherapy and Pharmacology|February 3, 2005
Endoxifen (4-hydroxy-N-desmethyl-tamoxifen) has anti-estrogenic effects in breast cancer cells with potency similar to 4-hydroxy-tamoxifenYoung Chai Lim, Zeruesenay Desta, David A Flockhart, et al.The Oncologist|February 16, 2006
Interethnic differences in genetic polymorphisms of CYP2D6 in the U.S. population: clinical implicationsStephen Bernard, Kathleen A Neville, Anne T Nguyen, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 16, 2002
Triethylenethiophosphoramide is a specific inhibitor of cytochrome P450 2B6: implications for cyclophosphamide metabolismJames M Rae, Nadia V Soukhova, David A Flockhart, et al.Journal of Medicinal Chemistry|June 5, 2013
Synthesis of mixed (E,Z)-, (E)-, and (Z)-norendoxifen with dual aromatase inhibitory and estrogen receptor modulatory activitiesWei Lv, Jinzhong Liu, Deshun Lu, et al.The Journal of Pharmacology and Experimental Therapeutics|October 29, 2004
The effects of tamoxifen and its metabolites on platelet function and release of reactive oxygen intermediatesOlga Vitseva, David A Flockhart, Yan Jin, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|October 15, 2015
Association of Variants in Candidate Genes with Lipid Profiles in Women with Early Breast Cancer on Adjuvant Aromatase Inhibitor TherapyCesar A Santa-Maria, Amanda Blackford, Anne T Nguyen, et al.Journal of Medicinal Chemistry|March 10, 2015
Design and synthesis of norendoxifen analogues with dual aromatase inhibitory and estrogen receptor modulatory activitiesWei Lv, Jinzhong Liu, Todd C Skaar, et al.Naunyn-Schmiedeberg'S Archives of Pharmacology|July 11, 2002
Teaching rational prescribing: a new clinical pharmacology curriculum for medical schoolsDavid A Flockhart, Sally Usdin Yasuda, John C Pezzullo, et al.Nature Reviews. Cancer|October 13, 2006
Breast cancer treatment and ovarian failure: risk factors and emerging genetic determinantsVered Stearns, Bryan Schneider, N Lynn Henry, et al.Pageof 15