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Journal of Medicinal Chemistry
|
March 5, 2009
Discovery of (S)-N-[2-[1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl] acetamide (apremilast), a potent and orally active phosphodiesterase 4 and tumor necrosis factor-alpha inhibitor
Hon-Wah Man, Peter Schafer, Lu Min Wong, et al.
Journal of Medicinal Chemistry
|
March 31, 2017
Protein Degradation via CRL4<sup>CRBN</sup> Ubiquitin Ligase: Discovery and Structure-Activity Relationships of Novel Glutarimide Analogs That Promote Degradation of Aiolos and/or GSPT1
Joshua D Hansen, Kevin Condroski, Matthew Correa, et al.
Journal of Medicinal Chemistry
|
April 21, 2017
A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos
Mary E Matyskiela, Weihong Zhang, Hon-Wah Man, et al.
Nature
|
July 2, 2015
Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS
Jan Krönke, Emma C Fink, Paul W Hollenbach, et al.
Blood
|
May 24, 2015
CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL
Patrick R Hagner, Hon-Wah Man, Celia Fontanillo, et al.
Page
of 2
Search research articles
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Showing results (11-20 of 15) with videos related to
Sort By:
Page
of 2
You have reached the last page of results.
This site can display upto 15 results.
Journal of Medicinal Chemistry
|
March 5, 2009
Discovery of (S)-N-[2-[1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl] acetamide (apremilast), a potent and orally active phosphodiesterase 4 and tumor necrosis factor-alpha inhibitor
Hon-Wah Man, Peter Schafer, Lu Min Wong, et al.
Journal of Medicinal Chemistry
|
March 31, 2017
Protein Degradation via CRL4<sup>CRBN</sup> Ubiquitin Ligase: Discovery and Structure-Activity Relationships of Novel Glutarimide Analogs That Promote Degradation of Aiolos and/or GSPT1
Joshua D Hansen, Kevin Condroski, Matthew Correa, et al.
Journal of Medicinal Chemistry
|
April 21, 2017
A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos
Mary E Matyskiela, Weihong Zhang, Hon-Wah Man, et al.
Nature
|
July 2, 2015
Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS
Jan Krönke, Emma C Fink, Paul W Hollenbach, et al.
Blood
|
May 24, 2015
CC-122, a pleiotropic pathway modifier, mimics an interferon response and has antitumor activity in DLBCL
Patrick R Hagner, Hon-Wah Man, Celia Fontanillo, et al.
Page
of 2