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Bioorganic & Medicinal Chemistry Letters
|
October 16, 2010
Discovery and synthesis of 6,7,8,9-tetrahydro-5H-pyrimido-[4,5-d]azepines as novel TRPV1 antagonists
Natalie A Hawryluk, Jeffrey E Merit, Alec D Lebsack, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 29, 2008
Identification and synthesis of 2,7-diamino-thiazolo[5,4-d]pyrimidine derivatives as TRPV1 antagonists
Alec D Lebsack, Bryan J Branstetter, Michael D Hack, et al.
Nature Communications
|
September 10, 2025
Pleistocene terrestrial warming trend in East Asia linked to Antarctic ice sheets growth
Huanye Wang, Weiguo Liu, Zhonghui Liu, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Synthesis and Pharmacological Characterization of Two Novel, Brain Penetrating P2X7 Antagonists
Michael A Letavic, Brian Lord, Francois Bischoff, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
January 8, 2024
Concurrent Asian monsoon strengthening and early modern human dispersal to East Asia during the last interglacial
Hong Ao, Jiaoyang Ruan, María Martinón-Torres, et al.
Journal of Medicinal Chemistry
|
August 23, 2016
Identification of (R)-(2-Chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyridin-2-yl)-4-methyl-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methanone (JNJ 54166060), a Small Molecule Antagonist of the P2X7 receptor
Devin M Swanson, Brad M Savall, Kevin J Coe, et al.
Nature Communications
|
October 17, 2020
Orbital climate variability on the northeastern Tibetan Plateau across the Eocene-Oligocene transition
Hong Ao, Guillaume Dupont-Nivet, Eelco J Rohling, et al.
European Journal of Pharmacology
|
May 18, 2011
Characterization of 2-(2,6-dichloro-benzyl)-thiazolo[5,4-d]pyrimidin-7-yl]-(4-trifluoromethyl-phenyl)-amine (JNJ-39729209) as a novel TRPV1 antagonist
Michael P Maher, Anindya Bhattacharya, Hong Ao, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 12, 2010
1,2-diamino-ethane-substituted-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepines as TRPV1 antagonists with improved properties
Alec D Lebsack, Jason C Rech, Bryan J Branstetter, et al.
Journal of Medicinal Chemistry
|
May 12, 2017
4-Methyl-6,7-dihydro-4H-triazolo[4,5-c]pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate
Michael A Letavic, Brad M Savall, Brett D Allison, et al.
Page
of 10
Search research articles
Search
Showing results (81-90 of 91) with videos related to
Sort By:
Page
of 10
Bioorganic & Medicinal Chemistry Letters
|
October 16, 2010
Discovery and synthesis of 6,7,8,9-tetrahydro-5H-pyrimido-[4,5-d]azepines as novel TRPV1 antagonists
Natalie A Hawryluk, Jeffrey E Merit, Alec D Lebsack, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 29, 2008
Identification and synthesis of 2,7-diamino-thiazolo[5,4-d]pyrimidine derivatives as TRPV1 antagonists
Alec D Lebsack, Bryan J Branstetter, Michael D Hack, et al.
Nature Communications
|
September 10, 2025
Pleistocene terrestrial warming trend in East Asia linked to Antarctic ice sheets growth
Huanye Wang, Weiguo Liu, Zhonghui Liu, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Synthesis and Pharmacological Characterization of Two Novel, Brain Penetrating P2X7 Antagonists
Michael A Letavic, Brian Lord, Francois Bischoff, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
January 8, 2024
Concurrent Asian monsoon strengthening and early modern human dispersal to East Asia during the last interglacial
Hong Ao, Jiaoyang Ruan, María Martinón-Torres, et al.
Journal of Medicinal Chemistry
|
August 23, 2016
Identification of (R)-(2-Chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyridin-2-yl)-4-methyl-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methanone (JNJ 54166060), a Small Molecule Antagonist of the P2X7 receptor
Devin M Swanson, Brad M Savall, Kevin J Coe, et al.
Nature Communications
|
October 17, 2020
Orbital climate variability on the northeastern Tibetan Plateau across the Eocene-Oligocene transition
Hong Ao, Guillaume Dupont-Nivet, Eelco J Rohling, et al.
European Journal of Pharmacology
|
May 18, 2011
Characterization of 2-(2,6-dichloro-benzyl)-thiazolo[5,4-d]pyrimidin-7-yl]-(4-trifluoromethyl-phenyl)-amine (JNJ-39729209) as a novel TRPV1 antagonist
Michael P Maher, Anindya Bhattacharya, Hong Ao, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 12, 2010
1,2-diamino-ethane-substituted-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepines as TRPV1 antagonists with improved properties
Alec D Lebsack, Jason C Rech, Bryan J Branstetter, et al.
Journal of Medicinal Chemistry
|
May 12, 2017
4-Methyl-6,7-dihydro-4H-triazolo[4,5-c]pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate
Michael A Letavic, Brad M Savall, Brett D Allison, et al.
Page
of 10