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Clinical and Translational Science
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July 8, 2024
A phase I thorough QT/QTc study evaluating therapeutic and supratherapeutic doses of avacopan in healthy participants
Shichang Miao, Peter Staehr, Ezra Tai, et al.
British Journal of Clinical Pharmacology
|
September 23, 2024
Concentration-QTc analysis of soticlestat in healthy adults: An alternative to a thorough QT study
Wei Yin, Nobuhito Dote, Hiroyuki Fukase, et al.
Clinical Pharmacology in Drug Development
|
July 29, 2023
Concentration-QTc Relationship from a Single Ascending Dose Study of ANAVEX3-71, a Novel Sigma-1 Receptor and Allosteric M1 Muscarinic Receptor Agonist in Development for the Treatment of Frontotemporal Dementia, Schizophrenia, and Alzheimer's Disease
Emmanuel O Fadiran, Edward Hammond, James Tran, et al.
Clinical Pharmacology in Drug Development
|
January 29, 2024
Concentration-QTcF Modeling of Icenticaftor from a Randomized, Placebo- and Positive-Controlled Thorough QT Study in Healthy Participants
Ganesh R Iyer, Borje Darpo, Hongqi Xue, et al.
Clinical Pharmacology in Drug Development
|
September 13, 2022
Evaluation of Deutetrabenazine's Potential to Delay Cardiac Repolarization Using Concentration-QTc Analysis
Frank Schneider, Borje Darpo, Pippa S Loupe, et al.
Progress in Neuro-Psychopharmacology & Biological Psychiatry
|
February 1, 2020
Combination of olanzapine and samidorphan has no clinically relevant effects on ECG parameters, including the QTc interval: Results from a phase 1 QT/QTc study
Lei Sun, Sergey Yagoda, Hongqi Xue, et al.
Clinical Pharmacology in Drug Development
|
December 11, 2019
Evaluation of Clinical Cardiac Safety of Itacitinib, a JAK1 Inhibitor, in Healthy Participants
Xiaohua Gong, Borje Darpo, Hongqi Xue, et al.
Clinical and Translational Science
|
March 8, 2020
No QTc Prolongation With Zanubrutinib: Results of Concentration-QTc Analysis From a Thorough QT Study in Healthy Subjects
Song Mu, Borje Darpo, Zhiyu Tang, et al.
Clinical and Translational Science
|
March 23, 2023
A randomized, single-dose, crossover study of the effects of ulotaront on electrocardiogram intervals in subjects with schizophrenia
Hironobu Tsukada, Snezana M Milanovic, Borje Darpo, et al.
Clinical and Translational Science
|
March 18, 2022
A thorough QTc study to evaluate the effects of oral rilzabrutinib administered alone and with ritonavir in healthy subjects
Sibel Ucpinar, Borje Darpo, Ann Neale, et al.
Page
of 5
Search research articles
Search
Showing results (31-40 of 45) with videos related to
Sort By:
Page
of 5
Clinical and Translational Science
|
July 8, 2024
A phase I thorough QT/QTc study evaluating therapeutic and supratherapeutic doses of avacopan in healthy participants
Shichang Miao, Peter Staehr, Ezra Tai, et al.
British Journal of Clinical Pharmacology
|
September 23, 2024
Concentration-QTc analysis of soticlestat in healthy adults: An alternative to a thorough QT study
Wei Yin, Nobuhito Dote, Hiroyuki Fukase, et al.
Clinical Pharmacology in Drug Development
|
July 29, 2023
Concentration-QTc Relationship from a Single Ascending Dose Study of ANAVEX3-71, a Novel Sigma-1 Receptor and Allosteric M1 Muscarinic Receptor Agonist in Development for the Treatment of Frontotemporal Dementia, Schizophrenia, and Alzheimer's Disease
Emmanuel O Fadiran, Edward Hammond, James Tran, et al.
Clinical Pharmacology in Drug Development
|
January 29, 2024
Concentration-QTcF Modeling of Icenticaftor from a Randomized, Placebo- and Positive-Controlled Thorough QT Study in Healthy Participants
Ganesh R Iyer, Borje Darpo, Hongqi Xue, et al.
Clinical Pharmacology in Drug Development
|
September 13, 2022
Evaluation of Deutetrabenazine's Potential to Delay Cardiac Repolarization Using Concentration-QTc Analysis
Frank Schneider, Borje Darpo, Pippa S Loupe, et al.
Progress in Neuro-Psychopharmacology & Biological Psychiatry
|
February 1, 2020
Combination of olanzapine and samidorphan has no clinically relevant effects on ECG parameters, including the QTc interval: Results from a phase 1 QT/QTc study
Lei Sun, Sergey Yagoda, Hongqi Xue, et al.
Clinical Pharmacology in Drug Development
|
December 11, 2019
Evaluation of Clinical Cardiac Safety of Itacitinib, a JAK1 Inhibitor, in Healthy Participants
Xiaohua Gong, Borje Darpo, Hongqi Xue, et al.
Clinical and Translational Science
|
March 8, 2020
No QTc Prolongation With Zanubrutinib: Results of Concentration-QTc Analysis From a Thorough QT Study in Healthy Subjects
Song Mu, Borje Darpo, Zhiyu Tang, et al.
Clinical and Translational Science
|
March 23, 2023
A randomized, single-dose, crossover study of the effects of ulotaront on electrocardiogram intervals in subjects with schizophrenia
Hironobu Tsukada, Snezana M Milanovic, Borje Darpo, et al.
Clinical and Translational Science
|
March 18, 2022
A thorough QTc study to evaluate the effects of oral rilzabrutinib administered alone and with ritonavir in healthy subjects
Sibel Ucpinar, Borje Darpo, Ann Neale, et al.
Page
of 5