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Diabetes, Obesity & Metabolism|November 4, 2024
Non-clinical and first-in-human characterization of ECC5004/AZD5004, a novel once-daily, oral small-molecule GLP-1 receptor agonistAmina Z Haggag, Jianfeng Xu, Laurie Butcher, et al.Nature Communications|September 13, 2023
Genetically encoded discovery of perfluoroaryl macrocycles that bind to albumin and exhibit extended circulation in vivoJeffrey Y K Wong, Arunika I Ekanayake, Serhii Kharchenko, et al.NPJ Genomic Medicine|December 22, 2017
Familial STAG2 germline mutation defines a new human cohesinopathyFernanda C Soardi, Alice Machado-Silva, Natália D Linhares, et al.Nature Communications|June 5, 2026
Targeting fibroblast TXNDC5 resolves tumor desmoplasia and PD-1 resistance in colorectal cancer with mesenchymal traitsKai-Lin Cheng, Chih-I Chen, Shu-Han Yu, et al.ACS Central Science|February 27, 2023
Development of Highly Potent Noncovalent Inhibitors of SARS-CoV-2 3CLproNingke Hou, Lei Shuai, Lijing Zhang, et al.Kidney International|September 1, 2024
A randomized phase 2b trial examined the effects of the glucagon-like peptide-1 and glucagon receptor agonist cotadutide on kidney outcomes in patients with diabetic kidney diseaseViknesh Selvarajah, Darren Robertson, Lars Hansen, et al.Circulation|May 15, 2026
Laroprovstat, the First Oral Small-Molecule PCSK9 Inhibitor for the Treatment of Hypercholesterolemia: Results From a Randomized, Single-Blind, Placebo-Controlled Phase 1 Trial in Treatment-Naive PatientsRick B Vega, Gavin O'Mahony, April M Barbour, et al.Nature Communications|August 28, 2020
Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFβ signaling through TGFBR1 stabilizationTzu-Han Lee, Chih-Fan Yeh, Ying-Tung Lee, et al.Nature|July 16, 2020
Author Correction: Structure of human GABAB receptor in an inactive stateJinseo Park, Ziao Fu, Aurel Frangaj, et al.Nature|June 26, 2020
Structure of human GABAB receptor in an inactive stateJinseo Park, Ziao Fu, Aurel Frangaj, et al.Pageof 59