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SLAS Discovery : Advancing Life Sciences R & D
|
September 29, 2017
A High-Throughput Dose-Response Cellular Thermal Shift Assay for Rapid Screening of Drug Target Engagement in Living Cells, Exemplified Using SMYD3 and IDO1
Dean E McNulty, William G Bonnette, Hongwei Qi, et al.
Molecular Pharmacology
|
October 7, 2015
Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1α Endoribonuclease Activity
Nestor O Concha, Angela Smallwood, William Bonnette, et al.
Journal of Medicinal Chemistry
|
September 11, 2015
Identification of Purines and 7-Deazapurines as Potent and Selective Type I Inhibitors of Troponin I-Interacting Kinase (TNNI3K)
Brian G Lawhorn, Joanne Philp, Yongdong Zhao, et al.
Protein Expression and Purification
|
May 12, 2010
Baculovirus production of fully-active phosphoinositide 3-kinase alpha as a p85alpha-p110alpha fusion for X-ray crystallographic analysis with ATP competitive enzyme inhibitors
Robert H Sinnamon, Patrick McDevitt, Beth L Pietrak, et al.
Bioorganic & Medicinal Chemistry
|
January 11, 2019
Discovery of a crystalline sulforaphane analog with good solid-state stability and engagement of the Nrf2 pathway in vitro and in vivo
Jeffrey Boehm, Roderick Davis, Claudia E Murar, et al.
Prostaglandins & Other Lipid Mediators
|
February 26, 2013
In vitro and in vivo characterization of a novel soluble epoxide hydrolase inhibitor
Patricia L Podolin, Brian J Bolognese, Joseph F Foley, et al.
Nature Chemical Biology
|
October 6, 2015
New IDH1 mutant inhibitors for treatment of acute myeloid leukemia
Ujunwa C Okoye-Okafor, Boris Bartholdy, Jessy Cartier, et al.
Nature Communications
|
July 14, 2018
Author Correction: Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening
Carl A Machutta, Christopher S Kollmann, Kenneth E Lind, et al.
Nature Communications
|
July 18, 2017
Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening
Carl A Machutta, Christopher S Kollmann, Kenneth E Lind, et al.
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of 3
Search research articles
Search
Showing results (21-30 of 29) with videos related to
Sort By:
Page
of 3
You have reached the last page of results.
This site can display upto 29 results.
SLAS Discovery : Advancing Life Sciences R & D
|
September 29, 2017
A High-Throughput Dose-Response Cellular Thermal Shift Assay for Rapid Screening of Drug Target Engagement in Living Cells, Exemplified Using SMYD3 and IDO1
Dean E McNulty, William G Bonnette, Hongwei Qi, et al.
Molecular Pharmacology
|
October 7, 2015
Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1α Endoribonuclease Activity
Nestor O Concha, Angela Smallwood, William Bonnette, et al.
Journal of Medicinal Chemistry
|
September 11, 2015
Identification of Purines and 7-Deazapurines as Potent and Selective Type I Inhibitors of Troponin I-Interacting Kinase (TNNI3K)
Brian G Lawhorn, Joanne Philp, Yongdong Zhao, et al.
Protein Expression and Purification
|
May 12, 2010
Baculovirus production of fully-active phosphoinositide 3-kinase alpha as a p85alpha-p110alpha fusion for X-ray crystallographic analysis with ATP competitive enzyme inhibitors
Robert H Sinnamon, Patrick McDevitt, Beth L Pietrak, et al.
Bioorganic & Medicinal Chemistry
|
January 11, 2019
Discovery of a crystalline sulforaphane analog with good solid-state stability and engagement of the Nrf2 pathway in vitro and in vivo
Jeffrey Boehm, Roderick Davis, Claudia E Murar, et al.
Prostaglandins & Other Lipid Mediators
|
February 26, 2013
In vitro and in vivo characterization of a novel soluble epoxide hydrolase inhibitor
Patricia L Podolin, Brian J Bolognese, Joseph F Foley, et al.
Nature Chemical Biology
|
October 6, 2015
New IDH1 mutant inhibitors for treatment of acute myeloid leukemia
Ujunwa C Okoye-Okafor, Boris Bartholdy, Jessy Cartier, et al.
Nature Communications
|
July 14, 2018
Author Correction: Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening
Carl A Machutta, Christopher S Kollmann, Kenneth E Lind, et al.
Nature Communications
|
July 18, 2017
Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening
Carl A Machutta, Christopher S Kollmann, Kenneth E Lind, et al.
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of 3