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Biorxiv : the Preprint Server for Biology|August 8, 2025
Small Molecule-Based Blockade of CD28 Suppresses T Cell Costimulation Across Cellular and Mucosal Co-culture ModelsSaurabh Upadhyay, Valerij Talagayev, Sungwoo Cho, et al.
European Journal of Medicinal Chemistry|September 24, 2025
Structure-based virtual screening identifies potent CD28 inhibitors that suppress T cell co-stimulation in cellular and mucosal modelsSaurabh Upadhyay, Valerij Talagayev, Sungwoo Cho, et al.
Biorxiv : the Preprint Server for Biology|February 12, 2026
Exploiting NMR Ensemble Heterogeneity Enables Small Molecule Discovery Against Dynamic Protein-Protein InterfacesHossam Nada, Sungwoo Cho, Ashraf N Abdo, et al.
Bioorganic & Medicinal Chemistry Letters|October 6, 2025
Design and validation of the first-in-class PROTACs for targeted degradation of the immune checkpoint LAG-3Nelson García Vázquez, Somaya A Abdel-Rahman, Hossam Nada, et al.
International Journal of Biological Macromolecules|March 13, 2026
Restoring amyloid clearance: Z17 promotes astrocytes to clear Alzheimer's plaques via CHI3L1 inhibitionHossam Nada, Longfei Zhang, Baljit Kaur, et al.
Biorxiv : the Preprint Server for Biology|December 19, 2025
Restoring Amyloid Clearance via Astrocytes: Z17 Is a Selective Inhibitor of CHI3L1 in Alzheimers DiseaseHossam Nada, Longfei Zhang, Baljit Kaur, et al.
Biorxiv : the Preprint Server for Biology|August 6, 2025
Virtual Screening-Guided Discovery of Small Molecule CHI3L1 Inhibitors with Functional Activity in Glioblastoma SpheroidsBaljit Kaur, Katrin Denzinger, Longfei Zhang, et al.
ACS Medicinal Chemistry Letters|November 19, 2025
Virtual Screening-Guided Discovery of Small-Molecule CHI3L1 Inhibitors with Functional Activity in Glioblastoma SpheroidsBaljit Kaur, Katrin Denzinger, Longfei Zhang, et al.
Biorxiv : the Preprint Server for Biology|April 10, 2026
LigandForge: A Web Server for Structure-Guided De Novo Drug DesignHossam Nada, Levente Sipos-Szabó, Dávid Bajusz, et al.
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