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Biorxiv : the Preprint Server for Biology|January 16, 2026
Quantitative analysis of genetic interactions in human cells from genome-wide CRISPR-Cas9 screensMaximilian Billmann, Michael Costanzo, Mahfuzur Rahman, et al.Genes & Development|August 22, 2025
UPR deficiency leads to poor growth, aneuploidy, and a trade-off between ER and general proteostasis in yeastConstantine Bartolutti, Allison J Kim, Yanzhe Ma, et al.Plos Computational Biology|March 11, 2011
Protein complexes are central in the yeast genetic landscapeMagali Michaut, Anastasia Baryshnikova, Michael Costanzo, et al.Developmental Cell|August 22, 2018
Essential Function of Mec1, the Budding Yeast ATM/ATR Checkpoint-Response Kinase, in Protein HomeostasisIsaac Corcoles-Saez, Kangzhen Dong, Anthony L Johnson, et al.Current Opinion in Microbiology|July 31, 2018
Integrating genetic and protein-protein interaction networks maps a functional wiring diagram of a cellBenjamin VanderSluis, Michael Costanzo, Maximilian Billmann, et al.Molecular Biology of the Cell|August 1, 2008
Genetic and structural analysis of Hmg2p-induced endoplasmic reticulum remodeling in Saccharomyces cerevisiaeChristine M Federovitch, Ying Z Jones, Amy H Tong, et al.The Journal of Biological Chemistry|September 9, 2008
Genetic and biochemical analysis of yeast and human cap trimethylguanosine synthase: functional overlap of 2,2,7-trimethylguanosine caps, small nuclear ribonucleoprotein components, pre-mRNA splicing factors, and RNA decay pathwaysStéphane Hausmann, Sushuang Zheng, Michael Costanzo, et al.Nature Reviews. Genetics|July 19, 2011
The future of model organisms in human disease researchTimothy J Aitman, Charles Boone, Gary A Churchill, et al.G3 (Bethesda, Md.)|June 7, 2015
CYCLoPs: A Comprehensive Database Constructed from Automated Analysis of Protein Abundance and Subcellular Localization Patterns in Saccharomyces cerevisiaeJudice L Y Koh, Yolanda T Chong, Helena Friesen, et al.Current Biology : CB|October 17, 2003
Formin leaky cap allows elongation in the presence of tight capping proteinsSally H Zigmond, Marie Evangelista, Charles Boone, et al.Pageof 34