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Epilepsia
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March 14, 2026
KCNJ4 variants disrupt inward-rectifier potassium channel function and cause refractory epilepsy
Hu Pan, Deng Liu, Wuhen Xu, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 8, 2013
Structure-based design of novel dihydroisoquinoline BACE-1 inhibitors that do not engage the catalytic aspartates
Simeon Bowers, Ying-zi Xu, Shendong Yuan, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 15, 2011
Design and synthesis of a novel, orally active, brain penetrant, tri-substituted thiophene based JNK inhibitor
Simeon Bowers, Anh P Truong, R Jeffrey Neitz, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 13, 2010
Design and synthesis of disubstituted thiophene and thiazole based inhibitors of JNK
Roy K Hom, Simeon Bowers, Jennifer M Sealy, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 9, 2009
Design and synthesis of cell potent BACE-1 inhibitors: structure-activity relationship of P1' substituents
Jennifer M Sealy, Anh P Truong, Luke Tso, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 17, 2010
Improving the permeability of the hydroxyethylamine BACE-1 inhibitors: structure-activity relationship of P2' substituents
Anh P Truong, Gary D Probst, Jose Aquino, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 30, 2010
Highly selective c-Jun N-terminal kinase (JNK) 2 and 3 inhibitors with in vitro CNS-like pharmacokinetic properties prevent neurodegeneration
Gary D Probst, Simeon Bowers, Jennifer M Sealy, et al.
Chemmedchem
|
June 25, 2013
Selective and brain-permeable polo-like kinase-2 (Plk-2) inhibitors that reduce α-synuclein phosphorylation in rat brain
Danielle L Aubele, Roy K Hom, Marc Adler, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 9, 2010
Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: structure-activity relationship of the aryl region
Gary D Probst, Simeon Bowers, Jennifer M Sealy, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 5, 2011
Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration
Simeon Bowers, Anh P Truong, R Jeffrey Neitz, et al.
Page
of 12
Search research articles
Search
Showing results (101-110 of 111) with videos related to
Sort By:
Page
of 12
Epilepsia
|
March 14, 2026
KCNJ4 variants disrupt inward-rectifier potassium channel function and cause refractory epilepsy
Hu Pan, Deng Liu, Wuhen Xu, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 8, 2013
Structure-based design of novel dihydroisoquinoline BACE-1 inhibitors that do not engage the catalytic aspartates
Simeon Bowers, Ying-zi Xu, Shendong Yuan, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 15, 2011
Design and synthesis of a novel, orally active, brain penetrant, tri-substituted thiophene based JNK inhibitor
Simeon Bowers, Anh P Truong, R Jeffrey Neitz, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 13, 2010
Design and synthesis of disubstituted thiophene and thiazole based inhibitors of JNK
Roy K Hom, Simeon Bowers, Jennifer M Sealy, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 9, 2009
Design and synthesis of cell potent BACE-1 inhibitors: structure-activity relationship of P1' substituents
Jennifer M Sealy, Anh P Truong, Luke Tso, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 17, 2010
Improving the permeability of the hydroxyethylamine BACE-1 inhibitors: structure-activity relationship of P2' substituents
Anh P Truong, Gary D Probst, Jose Aquino, et al.
Bioorganic & Medicinal Chemistry Letters
|
November 30, 2010
Highly selective c-Jun N-terminal kinase (JNK) 2 and 3 inhibitors with in vitro CNS-like pharmacokinetic properties prevent neurodegeneration
Gary D Probst, Simeon Bowers, Jennifer M Sealy, et al.
Chemmedchem
|
June 25, 2013
Selective and brain-permeable polo-like kinase-2 (Plk-2) inhibitors that reduce α-synuclein phosphorylation in rat brain
Danielle L Aubele, Roy K Hom, Marc Adler, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 9, 2010
Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: structure-activity relationship of the aryl region
Gary D Probst, Simeon Bowers, Jennifer M Sealy, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 5, 2011
Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration
Simeon Bowers, Anh P Truong, R Jeffrey Neitz, et al.
Page
of 12