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Cells|March 29, 2023
High-Throughput Screening Assay for Detecting Drug-Induced Changes in Synchronized Neuronal Oscillations and Potential Seizure Risk Based on Ca2+ Fluorescence Measurements in Human Induced Pluripotent Stem Cell (hiPSC)-Derived Neuronal 2D and 3D CulturesHua-Rong Lu, Manabu Seo, Mohamed Kreir, et al.
Channels (Austin, Tex.)|January 19, 2021
The resting membrane potential of hSC-CM in a syncytium is more hyperpolarised than that of isolated cellsDieter V Van de Sande, Ivan Kopljar, Alaerts Maaike, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|April 26, 2019
Assessing Drug-Induced Long QT and Proarrhythmic Risk Using Human Stem-Cell-Derived Cardiomyocytes in a Ca2+ Imaging Assay: Evaluation of 28 CiPA Compounds at Three Test SitesHua Rong Lu, Haoyu Zeng, Ralf Kettenhofen, et al.
Bioorganic & Medicinal Chemistry Letters|October 10, 2020
Hit-to-lead optimization and discovery of a potent, and orally bioavailable G protein coupled receptor kinase 2 (GRK2) inhibitorGuozhang Xu, Michael D Gaul, Zhijie Liu, et al.
Regulatory Toxicology and Pharmacology : RTP|August 22, 2020
Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendationsGary Gintant, Emily Pfeiffer Kaushik, Tromondae Feaster, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|May 3, 2018
Cross-Site Reliability of Human Induced Pluripotent stem cell-derived Cardiomyocyte Based Safety Assays Using Microelectrode Arrays: Results from a Blinded CiPA Pilot StudyDaniel Millard, Qianyu Dang, Hong Shi, et al.
Cell Reports|September 27, 2018
International Multisite Study of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Proarrhythmic Potential AssessmentKsenia Blinova, Qianyu Dang, Daniel Millard, et al.
Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology|December 2, 2015
Human-based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshopBlanca Rodriguez, Annamaria Carusi, Najah Abi-Gerges, et al.
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