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Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|February 25, 2010
Pharmacokinetic and pharmacodynamic modeling of an anti-interleukin-6 chimeric monoclonal antibody (siltuximab) in patients with metastatic renal cell carcinomaThomas Puchalski, Uma Prabhakar, Qun Jiao, et al.Journal of Pharmacokinetics and Pharmacodynamics|July 17, 2010
A latent variable approach for modeling categorical endpoints among patients with rheumatoid arthritis treated with golimumab plus methotrexateChuanpu Hu, Zhenhua Xu, Mahboob U Rahman, et al.Clinical Therapeutics|July 12, 2011
Pharmacokinetic properties of infliximab in children and adults with Crohn's disease: a retrospective analysis of data from 2 phase III clinical trialsAdedigbo A Fasanmade, Omoniyi J Adedokun, Marion Blank, et al.Journal of Clinical Pharmacology|July 13, 2010
Population approach for exposure-response modeling of golimumab in patients with rheumatoid arthritisChuanpu Hu, Zhenhua Xu, Yi Zhang, et al.The AAPS Journal|November 30, 2013
Mechanistic pharmacokinetic/target engagement/pharmacodynamic (PK/TE/PD) modeling in deciphering interplay between a monoclonal antibody and its soluble target in cynomolgus monkeysWeirong Wang, Xiaofeng Wang, Rajitha Doddareddy, et al.Journal of Clinical Pharmacology|November 26, 2009
Population-based exposure-efficacy modeling of ustekinumab in patients with moderate to severe plaque psoriasisHonghui Zhou, Chuanpu Hu, Yaowei Zhu, et al.Basic & Clinical Pharmacology & Toxicology|January 30, 2017
Modification of the Fc Region of a Human Anti-oncostatin M Monoclonal Antibody for Higher Affinity to FcRn Receptor and Extension of Half-life in Cynomolgus MonkeysIvo P Nnane, Chao Han, Qun Jiao, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 6, 2015
Pharmacokinetics and immunogenicity investigation of a human anti-interleukin-17 monoclonal antibody in non-naïve cynomolgus monkeysChao Han, George R Gunn, Joseph C Marini, et al.Clinical Therapeutics|December 3, 2014
Pharmacokinetic bridging approach for developing biologics-delivery devices: a case study with a golimumab autoinjectorZhenhua Xu, Stanley J Marciniak, Bart Frederick, et al.The Journal of Supportive Oncology|February 24, 2005
Are inflammatory cytokines the common link between cancer-associated cachexia and depression?James Illman, Robert Corringham, Don Robinson, et al.Pageof 6