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British Journal of Pharmacology|August 12, 2010
A new preclinical biomarker for risk of Torsades de Pointes: drug-induced reduction of the cardiac electromechanical windowHugo M VargasToxicological Sciences : an Official Journal of the Society of Toxicology|June 29, 2015
Proarrhythmia Risk Assessment in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Using the Maestro MEA PlatformYusheng Qu, Hugo M VargasJournal of Pharmacological and Toxicological Methods|May 27, 2009
A comparison of three software platforms for automated ECG analysisRay W Chui, Hugo M VargasClinical and Translational Science|May 21, 2025
Restraint-Based ECG and Arterial Pressure Assessment Do Not Reliably Detect Drug Induced QTc Prolongation and Hypotension: Evidence From Case StudiesKim A Henderson, Nicholas Ether, Hugo M VargasJournal of Pharmacological and Toxicological Methods|May 23, 2012
Comprehensive analysis of cardiac arrhythmias in telemetered cynomolgus monkeys over a 6 month periodRay W Chui, Katayoun Derakhchan, Hugo M VargasJournal of Pharmacological and Toxicological Methods|April 15, 2021
The in vivo QTc core assay: An evaluation of QTc variability, detection sensitivity and implications for the improvement of conscious dog and non-human primate telemetry studiesJoel Baublits, Hugo M Vargas, Michael J EngwallJournal of Pharmacological and Toxicological Methods|September 6, 2011
hERG potency estimates based upon dose solution analysis: What have we learned?Yusheng Qu, Paul Schnier, Roger Zanon, et al.Expert Opinion on Drug Safety|November 23, 2012
Nonclinical strategy considerations for safety pharmacology: evaluation of biopharmaceuticalsHugo M Vargas, Hamid R Amouzadeh, Michael J EngwallJournal of Pharmacological and Toxicological Methods|March 23, 2013
Human embryonic stem cell derived cardiac myocytes detect hERG-mediated repolarization effects, but not Nav1.5 induced depolarization delayYusheng Qu, Baoxi Gao, Mei Fang, et al.Handbook of Experimental Pharmacology|June 21, 2015
Safety Pharmacology Evaluation of BiopharmaceuticalsHamid R Amouzadeh, Michael J Engwall, Hugo M VargasPageof 7