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Hugues Dolgos

Showing results (1-10 of 23) with videos related to

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Clinical Pharmacokinetics|June 26, 2019
Requirements to Establishing Confidence in Physiologically Based Pharmacokinetic (PBPK) Models and Overcoming Some of the Challenges to Meeting ThemSheila Annie Peters, Hugues Dolgos
Current Opinion in Drug Discovery & Development|June 30, 2009
Physiologically based pharmacokinetic (PBPK) modeling and simulation: applications in lead optimizationSheila Annie Peters, Anna-Lena Ungell, Hugues Dolgos
Biopharmaceutics & Drug Disposition|February 3, 2017
A comparative evaluation of models to predict human intestinal metabolism from nonclinical dataEstelle Yau, Carl Petersson, Hugues Dolgos, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|June 20, 2019
Prediction of volume of distribution in humans: analysis of eight methods and their application in drug discoveryCarl Petersson, Orestis Papasouliotis, Marc Lecomte, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|May 1, 2013
Comparison of the in vitro and in vivo metabolism of Cladribine (Leustatin, Movectro) in animals and humanHolger Scheible, Marc Laisney, Elmar Wimmer, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 9, 2012
Evaluation of the use of static and dynamic models to predict drug-drug interaction and its associated variability: impact on drug discovery and early developmentSheila Annie Peters, Patricia E Schroeder, Nagdeep Giri, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|August 26, 2016
Comparison of methods for the prediction of human clearance from hepatocyte intrinsic clearance for a set of reference compounds and an external evaluation setTetsuo Yamagata, Ugo Zanelli, Dieter Gallemann, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|August 7, 2013
Utility of in vitro systems and preclinical data for the prediction of human intestinal first-pass metabolism during drug discovery and preclinical developmentFredrik H Karlsson, Salim Bouchene, Constanze Hilgendorf, et al.
Drug Discovery Today|January 26, 2020
Prediction of active human dose: learnings from 20 years of Merck KGaA experience, illustrated by case studiesSheila Annie Peters, Carl Petersson, Andree Blaukat, et al.
European Journal of Clinical Pharmacology|March 10, 2006
Investigation of sarizotan's impact on the pharmacokinetics of probe drugs for major cytochrome P450 isoenzymes: a combined cocktail trialSonja Krösser, Roland Neugebauer, Hugues Dolgos, et al.
Pageof 3

Showing results (1-10 of 23) with videos related to

Sort By:
Pageof 3
Clinical Pharmacokinetics|June 26, 2019
Requirements to Establishing Confidence in Physiologically Based Pharmacokinetic (PBPK) Models and Overcoming Some of the Challenges to Meeting ThemSheila Annie Peters, Hugues Dolgos
Current Opinion in Drug Discovery & Development|June 30, 2009
Physiologically based pharmacokinetic (PBPK) modeling and simulation: applications in lead optimizationSheila Annie Peters, Anna-Lena Ungell, Hugues Dolgos
Biopharmaceutics & Drug Disposition|February 3, 2017
A comparative evaluation of models to predict human intestinal metabolism from nonclinical dataEstelle Yau, Carl Petersson, Hugues Dolgos, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|June 20, 2019
Prediction of volume of distribution in humans: analysis of eight methods and their application in drug discoveryCarl Petersson, Orestis Papasouliotis, Marc Lecomte, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|May 1, 2013
Comparison of the in vitro and in vivo metabolism of Cladribine (Leustatin, Movectro) in animals and humanHolger Scheible, Marc Laisney, Elmar Wimmer, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 9, 2012
Evaluation of the use of static and dynamic models to predict drug-drug interaction and its associated variability: impact on drug discovery and early developmentSheila Annie Peters, Patricia E Schroeder, Nagdeep Giri, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|August 26, 2016
Comparison of methods for the prediction of human clearance from hepatocyte intrinsic clearance for a set of reference compounds and an external evaluation setTetsuo Yamagata, Ugo Zanelli, Dieter Gallemann, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|August 7, 2013
Utility of in vitro systems and preclinical data for the prediction of human intestinal first-pass metabolism during drug discovery and preclinical developmentFredrik H Karlsson, Salim Bouchene, Constanze Hilgendorf, et al.
Drug Discovery Today|January 26, 2020
Prediction of active human dose: learnings from 20 years of Merck KGaA experience, illustrated by case studiesSheila Annie Peters, Carl Petersson, Andree Blaukat, et al.
European Journal of Clinical Pharmacology|March 10, 2006
Investigation of sarizotan's impact on the pharmacokinetics of probe drugs for major cytochrome P450 isoenzymes: a combined cocktail trialSonja Krösser, Roland Neugebauer, Hugues Dolgos, et al.
Pageof 3