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Journal of the American Heart Association|September 29, 2020
Endothelial Cell Cystathionine γ-Lyase Expression Level Modulates Exercise Capacity, Vascular Function, and Myocardial Ischemia Reperfusion InjuryHuijing Xia, Zhen Li, Thomas E Sharp, et al.
Journal of the American College of Cardiology|October 21, 2017
Renal Sympathetic Denervation Protects the Failing Heart Via Inhibition of Neprilysin Activity in the KidneyDavid J Polhemus, Rishi K Trivedi, Juan Gao, et al.
Circulation Research|December 28, 2022
Hydrogen Sulfide Modulates Endothelial-Mesenchymal Transition in Heart FailureZhen Li, Huijing Xia, Thomas E Sharp, et al.
British Journal of Pharmacology|July 10, 2024
Adjunctive therapy with an oral H2S donor provides additional therapeutic benefit beyond SGLT2 inhibition in cardiometabolic heart failure with preserved ejection fractionJake E Doiron, Huijing Xia, Xiaoman Yu, et al.
Journal of the American Heart Association|February 8, 2023
Combination Sodium Nitrite and Hydralazine Therapy Attenuates Heart Failure With Preserved Ejection Fraction Severity in a "2-Hit" Murine ModelKyle B LaPenna, Zhen Li, Jake E Doiron, et al.
Circulation Research|June 15, 2022
Mitochondrial H2S Regulates BCAA Catabolism in Heart FailureZhen Li, Huijing Xia, Thomas E Sharp, et al.
JACC. Basic to Translational Science|August 16, 2025
Integrated Systems Biology Identifies Disruptions in Mitochondrial Function and Metabolism as Key Contributors to HFpEFAndrew A Gibb, Kyle LaPenna, Ryan B Gaspar, et al.
Biorxiv : the Preprint Server for Biology|November 1, 2024
Integrated systems biology identifies disruptions in mitochondrial function and metabolism as key contributors to heart failure with preserved ejection fraction (HFpEF)Andrew A Gibb, Kyle LaPenna, Ryan B Gaspar, et al.
Biorxiv : the Preprint Server for Biology|January 7, 2025
Dysregulation of Nitrosylation Dynamics Promotes Nitrosative Stress and Contributes to Cardiometabolic Heart Failure with Preserved Ejection FractionZhen Li, Kyle B LaPenna, Natalie D Gehred, et al.
JACC. Basic to Translational Science|August 7, 2025
Hydrogen Sulfide Deficiency and Therapeutic Targeting in Cardiometabolic HFpEF: Evidence for Synergistic Benefit With GLP-1/Glucagon AgonismJake E Doiron, Mahmoud H Elbatreek, Huijing Xia, et al.
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