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The Journal of Pharmacology and Experimental Therapeutics|January 31, 2016
Systems Pharmacology Analysis of the Amyloid Cascade after β-Secretase Inhibition Enables the Identification of an Aβ42 Oligomer PoolEline M T van Maanen, Tamara J van Steeg, Maria S Michener, et al.
The Journal of Pharmacology and Experimental Therapeutics|March 23, 2018
Extending a Systems Model of the APP Pathway: Separation of β- and γ-Secretase Sequential Cleavage Steps of APPEline M T van Maanen, Tamara J van Steeg, Maurice J Ahsman, et al.
Clinical and Translational Science|November 24, 2019
Making Better Dose Decisions: Using Exposure-Response Modeling to Integrate Efficacy Outcome of Two Phase IIb Clinical Trials of Ubrogepant for Migraine TreatmentChi-Chung Li, Tiffini Voss, Ken Kowalski, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|January 10, 2016
A PK-PD model-based assessment of sugammadex effects on coagulation parametersRolien Bosch, Marie-José van Lierop, Pieter-Jan de Kam, et al.
ERJ Open Research|December 2, 2020
Design and rationale of two phase 3 randomised controlled trials (COUGH-1 and COUGH-2) of gefapixant, a P2X3 receptor antagonist, in refractory or unexplained chronic coughDavid R Muccino, Alyn H Morice, Surinder S Birring, et al.
Journal of Clinical Pharmacology|May 16, 2024
Exposure-Response Analyses for Belzutifan to Inform Dosing Considerations and LabelingDhananjay D Marathe, Petra M Jauslin, Huub Jan Kleijn, et al.
Journal of Clinical Pharmacology|November 15, 2017
Population PK Analyses of Ubrogepant (MK-1602), a CGRP Receptor Antagonist: Enriching In-Clinic Plasma PK Sampling With Outpatient Dried Blood Spot SamplingChi-Chung Li, Marissa Dockendorf, Ken Kowalski, et al.
CPT: Pharmacometrics & Systems Pharmacology|August 19, 2023
Population pharmacokinetic analyses for belzutifan to inform dosing considerations and labelingDhananjay D Marathe, Petra M Jauslin, Huub Jan Kleijn, et al.
British Journal of Clinical Pharmacology|November 3, 2012
Early stage development of the glycine-1 re-uptake inhibitor SCH 900435: central nervous system effects compared with placebo in healthy menMarieke Liem-Moolenaar, Pierre Peeters, Ingrid M C Kamerling, et al.
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